Metformin is a widely used drug in today's prescriptions by physicians due to its specific
effects in treating and curing type II diabetes. Diabetes is a common disease that may occur …

Epidemiological studies suggest associations between diabetes mellitus and some cancers.
The risk of a number of cancers appears to be increased in diabetes mellitus. On the other …

Pancreatic cancer is the fourth leading cause of cancer-related death among men and
women in the United States. A major challenge in treatment remains patients' advanced …

Background and aims The positive and negative health effects of dietary carbohydrates are
of interest to both researchers and consumers. Methods International experts on …

Cardiovascular (CV) disease and cancer are the leading causes of death., Over the last
decades, it has been appreciated that both CV disease and cancer are more common in …

Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …

This systematic review and meta-analysis is the first to evaluate the evidence for an
association between metformin use and cancer outcomes in patients undergoing treatment …

Metabolic changes in cells that participate in inflammation, such as activated macrophages
and T-helper 17 cells, include a shift towards enhanced glucose uptake, glycolysis and …

Multiple epidemiological studies have documented an association between metformin, used
for treatment of type 2 diabetes, and reduced cancer incidence and mortality. Cell line …

Insulin resistance (IR) and hyperinsulinemia are hallmarks of the metabolic syndrome, as
are central adiposity, dyslipidemia, and a predisposition to type 2 diabetes, atherosclerotic …