[HTML][HTML] Digestive profiles of human milk, recombinant human and bovine lactoferrin: comparing the retained intact protein and peptide release

BJ Kim, RF Kuhfeld, JL Haas, YM Anaya, RR Martinez… - Nutrients, 2024 - mdpi.com
Lactoferrin (LF) is a major component of human milk. LF supplementation (currently bovine)
supports the immune system and helps maintain iron homeostasis in adults. No recombinant …

[HTML][HTML] Survival of intact bovine whey proteins across in vivo and simulated static in vitro models of the adult gastrointestinal tract

S Sutantawong, BJ Kim, Y Qu, DC Dallas - Food Chemistry, 2025 - Elsevier
Bovine whey contains bioactive proteins that could benefit consumer health, but their intact
bioactivity depends on their ability to survive the digestive process and remain intact to their …

Neonatal enteroids absorb extracellular vesicles from human milk‐fed infant digestive fluid

C Yung, Y Zhang, M Kuhn, RJ Armstrong… - Journal of …, 2024 - Wiley Online Library
Human milk contains extracellular vesicles (HMEVs). Pre‐clinical models suggest that
HMEVs may enhance intestinal function and limit inflammation; however, it is unknown if …

[HTML][HTML] Release of bioactive peptides from whey proteins across digestion in adult humans and a static in vitro digestion model

S Sutantawong, BJ Kim, RF Kuhfeld, Y Qu… - Journal of Functional …, 2024 - Elsevier
Proteolysis of whey proteins during gastrointestinal digestion releases bioactive peptides
with potential health benefits. Our study examined whey-derived peptide release after …

Urine inter‐alpha‐trypsin inhibitor family‐related proteins may serve as biomarkers for disease activity of lupus

J Jiang, J Zhao, Y Wang, D Liu… - Journal of Clinical …, 2022 - Wiley Online Library
Background Systemic lupus erythematosus (SLE) is a chronic inflammatory disease
involving multiple tissues. Inter‐Alpha‐Trypsin Inhibitor (ITI) family proteins have a role in …

Proteomics analysis reveals digestion‐resistant proteins from colostrum are associated with inflammatory and cytotoxic responses in intestinal epithelial cells

Y Chen, BJ Kim, DC Dallas - Journal of Parenteral and Enteral …, 2022 - Wiley Online Library
Background Although human‐milk feeding reduces the risk of necrotizing enterocolitis
(NEC) in preterm infants compared with formula feeding, the exact risk‐reduction …

Effect of digestion on stability of palivizumab IgG1 in the infant gastrointestinal tract

J Lueangsakulthai, BJ Kim, V Demers-Mathieu… - Pediatric …, 2021 - nature.com
Background Potentially, orally administered antibodies specific to enteric pathogens could
be administered to infants to prevent diarrheal infections, particularly in developing countries …

Identifying Differences in the Release of Bioactive Milk Peptides Across the Intestinal Tract Between Term and Preterm Infants

RL Beverly - 2021 - ir.library.oregonstate.edu
Premature birth interrupts the typical development of the human fetus, leaving the infant born
with underdeveloped gastrointestinal and immune systems. Preterm infants have reduced …

[PDF][PDF] Proteomics analysis reveals digestion-resistant proteins from colostrum are associated with inflammatory and cytotoxic responses in intestinal epithelial cells

C David - 2021 - dallaslab.org
Background: Although human-milk feeding reduces the risk of necrotizing enterocolitis
(NEC) in preterm infants compared with formula feeding, the exact riskreduction mechanism …