[HTML][HTML] Challenges for biophysical modeling of microstructure

IO Jelescu, M Palombo, F Bagnato… - Journal of Neuroscience …, 2020 - Elsevier
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Combined diffusion‐relaxometry microstructure imaging: Current status and future prospects

PJ Slator, M Palombo, KL Miller… - Magnetic resonance …, 2021 - Wiley Online Library
Microstructure imaging seeks to noninvasively measure and map microscopic tissue
features by pairing mathematical modeling with tailored MRI protocols. This article reviews …

Microstructural imaging of the human brain with a 'super-scanner': 10 key advantages of ultra-strong gradients for diffusion MRI

DK Jones, DC Alexander, R Bowtell, M Cercignani… - NeuroImage, 2018 - Elsevier
The key component of a microstructural diffusion MRI 'super-scanner'is a dedicated high-
strength gradient system that enables stronger diffusion weightings per unit time compared …

Diffuse axonal injury has a characteristic multidimensional MRI signature in the human brain

D Benjamini, D Iacono, ME Komlosh, DP Perl… - Brain, 2021 - academic.oup.com
Axonal injury is a major contributor to the clinical symptomatology in patients with traumatic
brain injury. Conventional neuroradiological tools, such as CT and MRI, are insensitive to …

Integrated and efficient diffusion-relaxometry using ZEBRA

J Hutter, PJ Slator, D Christiaens, RPAG Teixeira… - Scientific reports, 2018 - nature.com
The emergence of multiparametric diffusion models combining diffusion and relaxometry
measurements provides powerful new ways to explore tissue microstructure, with the …

Mapping astrogliosis in the individual human brain using multidimensional MRI

D Benjamini, DS Priemer, DP Perl, DL Brody… - Brain, 2023 - academic.oup.com
There are currently no non-invasive imaging methods available for astrogliosis assessment
or mapping in the central nervous system despite its essential role in the response to many …

Mapping the human connectome using diffusion MRI at 300 mT/m gradient strength: Methodological advances and scientific impact

Q Fan, C Eichner, M Afzali, L Mueller, CMW Tax… - Neuroimage, 2022 - Elsevier
Tremendous efforts have been made in the last decade to advance cutting-edge MRI
technology in pursuit of mapping structural connectivity in the living human brain with …

Combined diffusion‐relaxometry MRI to identify dysfunction in the human placenta

PJ Slator, J Hutter, M Palombo… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose A combined diffusion‐relaxometry MR acquisition and analysis pipeline for in vivo
human placenta, which allows for exploration of coupling between and apparent diffusion …

Computing and visualising intra‐voxel orientation‐specific relaxation–diffusion features in the human brain

JP de Almeida Martins, CMW Tax… - Human brain …, 2021 - Wiley Online Library
Diffusion MRI techniques are used widely to study the characteristics of the human brain
connectome in vivo. However, to resolve and characterise white matter (WM) fibres in …

[HTML][HTML] MTE-NODDI: Multi-TE NODDI for disentangling non-T2-weighted signal fractions from compartment-specific T2 relaxation times

T Gong, Q Tong, H He, Y Sun, J Zhong, H Zhang - Neuroimage, 2020 - Elsevier
Neurite orientation dispersion and density imaging (NODDI) has become a popular diffusion
MRI technique for investigating microstructural alternations during brain development …