Cancer progress and priorities: lung cancer

MB Schabath, ML Cote - Cancer epidemiology, biomarkers & prevention, 2019 - AACR
In the United States, lung cancer is the second most common diagnosed cancer and the
leading cause of cancer-related death. Although tobacco smoking is the major risk factor …

Is asbestos still a problem in the world? A current review

LP Thives, E Ghisi, JJT Júnior, AS Vieira - Journal of environmental …, 2022 - Elsevier
Asbestos has been used by automobile, construction, manufacturing, power, and chemical
industries for many years due to its particular properties, ie high tensile strength, non …

[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics

H Padinharayil, J Varghese, MC John, GK Rajanikant… - Genes & …, 2023 - Elsevier
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …

[HTML][HTML] AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells

H Li, Z Liu, L Liu, H Zhang, C Han, L Girard, H Park… - Cell Reports …, 2022 - cell.com
Mutations in STK11/LKB1 in non-small cell lung cancer (NSCLC) are associated with poor
patient responses to immune checkpoint blockade (ICB), and introduction of a Stk11/Lkb1 …

Association between serum copper/zinc ratio and lung cancer: A systematic review with meta-analysis

L Zhang, J Shao, SW Tan, HP Ye, XY Shan - Journal of Trace Elements in …, 2022 - Elsevier
Background Numerous studies have investigated the relationship between serum
copper/zinc ratio and lung cancer. However, the results are inconsistent. Therefore, we …

Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy

F Luberto, D Ferrante, S Silvestri, A Angelini… - Environmental …, 2019 - Springer
Background Despite the available information on cancer risk, asbestos is used in large
areas in the world, mostly in the production of asbestos cement. Moreover, questions are …

Occupational exposure to nickel and hexavalent chromium and the risk of lung cancer in a pooled analysis of case‐control studies (SYNERGY)

T Behrens, C Ge, R Vermeulen… - … journal of cancer, 2023 - Wiley Online Library
There is limited evidence regarding the exposure‐effect relationship between lung‐cancer
risk and hexavalent chromium (Cr (VI)) or nickel. We estimated lung‐cancer risks in relation …

[HTML][HTML] Current and new challenges in occupational lung diseases

S De Matteis, D Heederik, A Burdorf… - European …, 2017 - Eur Respiratory Soc
Occupational lung diseases are an important public health issue and are avoidable through
preventive interventions in the workplace. Up-to-date knowledge about changes in exposure …

Asbestos, smoking and lung cancer: an update

S Klebe, J Leigh, DW Henderson… - International Journal of …, 2020 - mdpi.com
This review updates the scientific literature concerning asbestos and lung cancer,
emphasizing cumulative exposure and synergism between asbestos exposure and tobacco …

Respirable crystalline silica exposure, smoking, and lung cancer subtype risks. A pooled analysis of case–control studies

C Ge, S Peters, A Olsson, L Portengen… - American Journal of …, 2020 - atsjournals.org
Rationale: Millions of workers around the world are exposed to respirable crystalline silica.
Although silica is a confirmed human lung carcinogen, little is known regarding the cancer …