Metastases are the main type of malignancy involving bone, which is the third most frequent
site of metastatic carcinoma, after lung and liver. Skeletal-related events such as intractable …

Bones are the third most common site of metastatic disease. Treatment is rarely curative;
rather, it seeks to control disease progression and palliate symptoms. Imaging evaluation of …

High intensity focused ultrasound (HIFU) systems have been approved for therapeutic
ultrasound delivery to cause tissue ablation or induced hyperthermia. Microbubble agents …

Magnetic resonance-guided high intensity focused ultrasound (MRgHIFU) is an established
method for producing localized hyperthermia. Given the real-time imaging and acoustic …

Oligometastatic soft tissue sarcoma represents an intermediate state between localized and
disseminated disease. Combination A combination of surgery, radiotherapy and systemic …

Purpose To analyze the effectiveness of image-guided energy ablation techniques with and
without concurrent therapies in providing palliative pain relief in patients with bone …

Bone metastases are common complications of solid tumors. The outcome is poor despite
major progress in cancer therapies. We describe a multicenter, open-label, phase 1, dose …

Breast tumors, both benign and malignant, persist as a widespread and intricate health
challenge on a global scale. In particular, breast cancer is now the most frequently …

Giant cell tumors of bone are a rare entity, usually occurring in young patients and
characteristically arising in the long bones. The spinal location is rare and usually presents …

Simple Summary High Intensity Focused Ultrasound (HIFU) allows non-invasive ablation of
tumors and denervation of painful bone lesions. For 20 years, this method has been used for …