One immune cell to bind them all: platelet contribution to neurodegenerative disease

G Rodriguez Moore, I Melo-Escobar, D Stegner… - Molecular …, 2024 - Springer
Alzheimer's disease (AD) and related dementias (ADRD) collectively affect a significant
portion of the aging population worldwide. The pathological progression of AD involves not …

[HTML][HTML] The Well-Forgotten Old: Platelet-Rich Plasma in Modern Anti-Aging Therapy

AV Gorodilova, CB Kharisova, MN Osinnikova… - Cells, 2024 - mdpi.com
Currently, approaches to personalized medicine are actively developing. For example, the
use of platelet-rich plasma (PRP) is actively growing every year. As a result of activation …

The differential formation and composition of leukocyte-platelet aggregates induced by various cellular stimulants

AD Peshkova, SM Saliakhutdinova, K Sounbuli… - Thrombosis …, 2024 - Elsevier
Background Leukocyte-platelet aggregates comprise a pathogenic link between hemostasis
and immunity, but the prerequisites and mechanisms of their formation remain not …

[HTML][HTML] The molecular mechanisms of portal vein thrombosis in hepatocellular carcinoma

L Galasso, L Cerrito, F Termite, I Mignini, G Esposto… - Cancers, 2024 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) associated with portal vein thrombosis
(PVT) represents an advanced stage of the tumor, with a subsequently poor prognosis and …

Platelets in Kawasaki disease: mediators of vascular inflammation

M Noval Rivas, B Kocatürk, BS Franklin… - Nature Reviews …, 2024 - nature.com
Kawasaki disease, a systemic vasculitis that affects young children and can result in
coronary artery aneurysms, is the leading cause of acquired heart disease among children …

Platelet activation through CD62P and the formation of platelet–monocyte complexes are associated with the exacerbation of mucosal inflammation in patients with …

Y Sano, T Tomiyama, N Yagi, Y Ito, Y Honzawa… - Scientific Reports, 2024 - nature.com
Ulcerative colitis (UC) is a refractory, chronic inflammatory bowel disease of unknown
etiology. Although platelets are activated in UC, their relevance in pathophysiology remains …

Downregulation of cardiac inflammation via the CaMKII δ/NF-κB pathway in heart failure by Lonicerae Japonicae Flos and Angelicae Sinensis Radix

J Tang, X Li, X Yu, D Wang, K Huang, H Pu, J Yu, S Li… - Phytomedicine, 2025 - Elsevier
Background Inflammation serves an essential function in the occurrence and progression of
heart failure (HF), especially in the early stage. Lonicerae japonicae Flos (LJF), Angelicae …

Nerve pathology of microangiopathy and thromboinflammation in hereditary transthyretin amyloidosis

SJ Yeh, TY Yeh, YS Wang, CC Chao… - Annals of Clinical …, 2024 - Wiley Online Library
Objective Despite amyloid deposition as a hallmark of hereditary transthyretin amyloidosis
(ATTRv) with polyneuropathy, this pathology could not completely account for nerve …

microRNAs and thrombo-inflammation: relationship in sight

S Águila, R González-Conejero… - Current Opinion in …, 2024 - journals.lww.com
Targeting microRNAs is a promising therapeutic approach to control thrombosis in patients
with both infectious and noninfectious inflammatory diseases. Future research efforts should …

To Gain Insights into the Pathophysiological Mechanisms of the Thrombo-Inflammatory Process in the Atherosclerotic Plaque

F Nappi - International Journal of Molecular Sciences, 2023 - mdpi.com
Thromboinflammation, the interplay between thrombosis and inflammation, is a significant
pathway that drives cardiovascular and autoimmune diseases, as well as COVID-19. SARS …