Dance with the devil: stress granules and signaling in antiviral responses

N Eiermann, K Haneke, Z Sun, G Stoecklin, A Ruggieri - Viruses, 2020 - mdpi.com
Cells have evolved highly specialized sentinels that detect viral infection and elicit an
antiviral response. Among these, the stress-sensing protein kinase R, which is activated by …

Viral internal ribosomal entry sites: four classes for one goal

J Mailliot, F Martin - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
To ensure efficient propagation, viruses need to rapidly produce viral proteins after cell
entrance. Since viral genomes do not encode any components of the protein biosynthesis …

PLK1-ELAVL1/HuR-miR-122 signaling facilitates hepatitis C virus proliferation

Y Seo, Y Kang, Y Ham, MH Kim… - Proceedings of the …, 2022 - National Acad Sciences
The liver-specific microRNA, miR-122, plays an essential role in the propagation of hepatitis
C virus (HCV) by binding directly to the 5′-end of its genomic RNA. Despite its significance …

Respiratory syncytial virus induces host RNA stress granules to facilitate viral replication

ME Lindquist, AW Lifland, TJ Utley… - Journal of …, 2010 - Am Soc Microbiol
Mammalian cell cytoplasmic RNA stress granules are induced during various conditions of
stress and are strongly associated with regulation of host mRNA translation. Several viruses …

Zika virus subverts stress granules to promote and restrict viral gene expression

G Bonenfant, N Williams, R Netzband… - Journal of …, 2019 - Am Soc Microbiol
Flaviviruses limit the cell stress response by preventing the formation of stress granules
(SGs) and modulate viral gene expression by subverting different proteins involved in the …

[HTML][HTML] HIV Rev assembly on the Rev response element (RRE): a structural perspective

JW Rausch, SFJ Le Grice - Viruses, 2015 - mdpi.com
HIV-1 Rev is an~ 13 kD accessory protein expressed during the early stage of virus
replication. After translation, Rev enters the nucleus and binds the Rev response element …

Heterogeneous nuclear ribonucleoprotein K promotes cap-independent translation initiation of retroviral mRNAs

Y Fuentes, V Olguín, B López-Ulloa… - Nucleic Acids …, 2024 - academic.oup.com
Translation initiation of the human immunodeficiency virus-type 1 (HIV-1) genomic mRNA
(vRNA) is cap-dependent or mediated by an internal ribosome entry site (IRES). The HIV-1 …

Hepatitis C virus translation regulation

M Niepmann, GK Gerresheim - International journal of molecular sciences, 2020 - mdpi.com
Translation of the hepatitis C virus (HCV) RNA genome is regulated by the internal ribosome
entry site (IRES), located in the 5'-untranslated region (5′ UTR) and part of the core protein …

Sindbis virus usurps the cellular HuR protein to stabilize its transcripts and promote productive infections in mammalian and mosquito cells

KJ Sokoloski, AM Dickson, EL Chaskey, NL Garneau… - Cell host & …, 2010 - cell.com
How viral transcripts are protected from the cellular RNA decay machinery and the
importance of this protection for the virus are largely unknown. We demonstrate that Sindbis …

HIV-1 replication and the cellular eukaryotic translation apparatus

S Guerrero, J Batisse, C Libre, S Bernacchi, R Marquet… - Viruses, 2015 - mdpi.com
Eukaryotic translation is a complex process composed of three main steps: initiation,
elongation, and termination. During infections by RNA-and DNA-viruses, the eukaryotic …