Estrogen receptors regulate innate immune cells and signaling pathways

S Kovats - Cellular immunology, 2015 - Elsevier
Humans show strong sex differences in immunity to infection and autoimmunity, suggesting
sex hormones modulate immune responses. Indeed, receptors for estrogens (ERs) regulate …

The impact of estrogens and their receptors on immunity and inflammation during infection

AT Harding, NS Heaton - Cancers, 2022 - mdpi.com
Simple Summary Human health is significantly affected by microbial infections. One of the
largest determinants of the outcomes of such infections is the host immune response. Too …

Estrogen, angiogenesis, immunity and cell metabolism: solving the puzzle

A Trenti, S Tedesco, C Boscaro, L Trevisi… - International journal of …, 2018 - mdpi.com
Estrogen plays an important role in the regulation of cardiovascular physiology and the
immune system by inducing direct effects on multiple cell types including immune and …

Estrogen signaling in metabolic inflammation

R Monteiro, D Teixeira, C Calhau - Mediators of inflammation, 2014 - Wiley Online Library
There is extensive evidence supporting the interference of inflammatory activation with
metabolism. Obesity, mainly visceral obesity, is associated with a low‐grade inflammatory …

Maternal immune activation as an epidemiological risk factor for neurodevelopmental disorders: Considerations of timing, severity, individual differences, and sex in …

MB Hall, DE Willis, EL Rodriguez… - Frontiers in …, 2023 - frontiersin.org
Epidemiological evidence suggests that one's risk of being diagnosed with a
neurodevelopmental disorder (NDD)—such as autism, ADHD, or schizophrenia—increases …

Estrogen anti-inflammatory activity on human monocytes is mediated through cross-talk between estrogen receptor ERα36 and GPR30/GPER1

V Pelekanou, M Kampa, F Kiagiadaki… - Journal of Leucocyte …, 2016 - academic.oup.com
Estrogens are known modulators of monocyte/macrophage functions; however, the
underlying mechanism has not been clearly defined. Recently, a number of estrogen …

Sex-based aortic dissection outcomes from the International Registry of Acute Aortic Dissection

LV Huckaby, I Sultan, S Trimarchi, B Leshnower… - The Annals of thoracic …, 2022 - Elsevier
Background Worse outcomes have been reported for women with type A acute aortic
dissection (TAAD). We sought to determine sex-specific operative approaches and …

The effects of estrogen in ischemic stroke

EC Koellhoffer, LD McCullough - Translational stroke research, 2013 - Springer
Stroke is a leading cause of death and the most common cause of long-term disability in the
USA. Women have a lower incidence of stroke compared with men throughout most of the …

[HTML][HTML] Short-term PM2. 5 exposure induces sustained pulmonary fibrosis development during post-exposure period in rats

B Sun, Y Shi, Y Li, J Jiang, S Liang, J Duan… - Journal of Hazardous …, 2020 - Elsevier
Up to now, while some toxicological studies have identified pulmonary fibrosis immediately
induced by long-term PM 2.5 exposure, there has been no evidence indicating, whether …

Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis

Y Gou, X Li, P Li, H Zhang, T Xu, H Wang… - Human …, 2019 - academic.oup.com
STUDY QUESTION How is the activation of estrogen receptor β (ERβ) in endometriotic
stromal cells (ESCs) involved in macrophage recruitment to promote the pathogenesis of …