Silkworm sericin: properties and biomedical applications

RI Kunz, RMC Brancalhão, LFC Ribeiro… - BioMed research …, 2016 - Wiley Online Library
Silk sericin is a natural polymer produced by silkworm, Bombyx mori, which surrounds and
keeps together two fibroin filaments in silk thread used in the cocoon. The recovery and …

Silk proteins for biomedical applications: Bioengineering perspectives

B Kundu, NE Kurland, S Bano, C Patra… - Progress in polymer …, 2014 - Elsevier
Biomaterials of either natural or synthetic origin are used to fabricate implantable devices, as
carriers for bioactive molecules or as substrates to facilitate tissue regeneration. For the …

Photo-crosslinkable, injectable sericin hydrogel as 3D biomimetic extracellular matrix for minimally invasive repairing cartilage

C Qi, J Liu, Y Jin, L Xu, G Wang, Z Wang, L Wang - Biomaterials, 2018 - Elsevier
Millions of patients worldwide suffer from cartilage injury and age/disease-related cartilage
degeneration. However, cartilage, such as articular cartilage, is poor at self-regeneration …

Designing scaffolds for corneal regeneration

M Ahearne, J Fernández‐Pérez… - Advanced Functional …, 2020 - Wiley Online Library
Corneal blindness is one of the most common causes of vision loss worldwide, affecting
millions of people. To treat these patients, researchers have been examining different …

Processing and characterization of silk sericin from Bombyx mori and its application in biomaterials and biomedicines

TT Cao, YQ Zhang - Materials Science and Engineering: C, 2016 - Elsevier
Bombyx mori silk is composed of 60–80% fibroin, 15–35% sericin and 1–5% non-sericin
component including wax, pigments, sugars and other impurities. For two decades, the …

Nonmulberry silk biopolymers

SC Kundu, B Kundu, S Talukdar, S Bano… - …, 2012 - Wiley Online Library
The silk produced by silkworms are biopolymers and can be classified into two types—
mulberry and nonmulberry. Mulberry silk of silkworm Bombyx mori has been extensively …

Advances in mechanical properties of hydrogels for cartilage tissue defect repair

W Wang, Y Shi, G Lin, B Tang, X Li… - Macromolecular …, 2023 - Wiley Online Library
Numerous factors, such as degeneration and accidents, frequently cause cartilage
deterioration. Owing to the absence of blood vessels and nerves in cartilage tissue, the …

Antioxidant potential of mulberry and non-mulberry silk sericin and its implications in biomedicine

JP Kumar, BB Mandal - Free Radical Biology and Medicine, 2017 - Elsevier
Sericin, a principal constituent of silk, is widely used in various biomedical applications. In
addition, conferring protection against free radicals and oxidative damage add more value to …

Synthesis, characterization and safety evaluation of sericin-based hydrogels for controlled delivery of acyclovir

MM Al-Tabakha, SA Khan, A Ashames, H Ullah… - Pharmaceuticals, 2021 - mdpi.com
Conventional formulations of antiviral drug acyclovir have various limitations such as low
bioavailability. The current study was aimed at developing polymeric matrices for the …

Sericins exhibit ROS-scavenging, anti-tyrosinase, anti-elastase, and in vitro immunomodulatory activities

T Chlapanidas, S Faragò, G Lucconi… - International journal of …, 2013 - Elsevier
Some biological properties of Bombyx mori sericins from twenty strains were investigated,
fourteen fed with artificial diet, two with fresh mulberry leaves and four with both diets …