Tuberculous meningitis (TBM) is the most severe form of TB. Despite treatment, mortality and
long-term disability remain unacceptably high. Prevention, early recognition, diagnosis and …

Childhood pulmonary TB (PTB) is under diagnosed, in part due to difficulties in obtaining
microbiological confirmation. However, given the poor specificity of clinical diagnosis …

Confirming the diagnosis of childhood tuberculosis is a major challenge. However, research
on childhood tuberculosis as it relates to better diagnostics is often neglected because of …

Background Tuberculosis (TB) in children is rarely confirmed due to the lack of effective
diagnostic tools; only 10 to 15% of pediatric TB is smear positive due to paucibacillary …

Mycobacterium tuberculosis infection remains a major cause of global mortality and
morbidity and the resulting disease, tuberculosis (TB), caused an estimated 1.7 million …

Rationale: Mortality is exceedingly high and rapid among patients infected with HIV and
tuberculosis (TB), in part because of limited access to appropriate TB diagnostics. The …

Methods Active scanning of the recent literature using the keywords:“children
tuberculosis”,“latent tuberculosis infection”,“new diagnosis tools” and “treatment modalities” …

Background: The diagnosis of childhood tuberculosis (TB) is complex and most of the new
diagnostics for TB are for adults. Aims: To review the performance of TB diagnostics and …

TB is a major public health problem causing 9 million cases, of which 10%–15% occur in
children each year. Historically, children have received lower priority within TB control …

Childhood TB diagnosis is challenging. Studies in adults suggest Microscopic Observation
Drug Susceptibility (MODS) culture or the Xpert MTB/RIF assay might be used to expand …