Heterotrimeric G-proteins are intracellular partners of G-protein-coupled receptors (GPCRs).
GPCRs act on inactive Gα· GDP/Gβγ heterotrimers to promote GDP release and GTP …

Posttranscriptional gene expression including splicing, RNA transport, translation, and RNA
decay provides an important regulatory layer in many if not all molecular pathways …

RNA transport is an important and fundamental event for local protein synthesis, especially
in neurons. RNA is transported as large granules, but little is known about them. Here, we …

Although subcellular mRNA trafficking has been demonstrated as a mechanism to control
protein distribution, it is generally believed that most protein localization occurs subsequent …

Asymmetric cell division (ACD) is an evolutionarily conserved mechanism used by
prokaryotes and eukaryotes alike to control cell fate and generate cell diversity. A detailed …

The p16INK4a cyclin-dependent kinase inhibitor is implicated in replicative senescence, the
state of permanent growth arrest provoked by cumulative cell divisions or as a response to …

Abstract Mammalian Staufen (Stau) 1 is an RNA binding protein that is thought to function in
mRNA transport and translational control. Nonsense-mediated mRNA decay (NMD) …

Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

Intracellular targeting of mRNAs has long been recognized as a means to produce proteins
locally, but has only recently emerged as a prevalent mechanism used by a wide variety of …

Background: Memory formation after olfactory learning in Drosophila displays behavioral
and molecular properties similar to those of other species. Particularly, long-term memory …