Incidence, risk factors, and prognosis of hidradenitis suppurativa across the globe: insights from the literature

HM Alotaibi - Clinical, Cosmetic and Investigational Dermatology, 2023 - Taylor & Francis
Hidradenitis suppurativa, a chronic inflammatory disease of the skin, affects a patient's
quality of life to a greater extent. While the disease burden, including its incidence and …

Obesity and hidradenitis suppurativa: targeting meta-inflammation for therapeutic gain

D Mintoff, R Agius, F Benhadou, A Das… - Clinical and …, 2023 - academic.oup.com
Hidradenitis suppurativa (HS) is a chronic, inflammatory condition of the pilosebaceous unit.
The typical patient with HS is characterized as someone with obesity, who smokes and who …

NCSTN in-frame deletion in Maltese patients with hidradenitis suppurativa

D Mintoff, NP Pace, I Borg - JAMA dermatology, 2023 - jamanetwork.com
Importance Hidradenitis suppurativa (HS) is a complex trait that has a monogenic etiology in
a subset of patients. Variation in genes that encode proteins of the γ secretase complex …

Platelet-rich plasma and acellular dermal matrix in the surgical treatment of hidradenitis suppurativa: a comparative retrospective study

M Gierek, A Klama-Baryła, W Łabuś… - Journal of Clinical …, 2023 - mdpi.com
(1) Introduction: Hidradenitis suppurativa (HS) is an inflammatory skin disease with
recurrent, chronic, painful, and purulent skin lesions. Topical or systemic antibiotics are the …

Serum immunoglobulin G is a marker of hidradenitis suppurativa disease severity

D Mintoff, I Borg, NP Pace - International Journal of Molecular Sciences, 2022 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic inflammatory condition of the skin that is brought
about by autoinflammation and hyperkeratosis at the pilosebaceous unit. The clinical …

Hidradenitis Suppurativa: An Interdisciplinary Problem in Dermatology, Gynecology, and Surgery—Pathogenesis, Comorbidities, and Current Treatments

A Nowak-Liduk, D Kitala, G Ochała-Gierek, W Łabuś… - Life, 2023 - mdpi.com
Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic inflammatory
disease that manifests as painful nodules, abscesses, draining dermal tunnels, and scarring …

Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression

KL Bursch, CJ Goetz, G Jiao, R Nuñez, MD Olp… - Journal of Biological …, 2024 - ASBMB
The polybromo, brahma-related gene 1–associated factors (PBAF) chromatin remodeling
complex subunit polybromo-1 (PBRM1) contains six bromodomains that recognize and bind …

[HTML][HTML] Comprehensive catalog of variants potentially associated with hidradenitis suppurativa, including newly identified variants from a cohort of 100 patients

K Muret, V Le Goff, C Dandine-Roulland… - International Journal of …, 2024 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic skin disease characterized by painful, recurrent
abscesses, nodules, and scarring, primarily in skin folds. The exact causes of HS are …

NOD2 at the interface of hidradenitis suppurativa and inflammatory bowel disease—An in silico analysis.

D Mintoff, I Borg, NP Pace - Experimental Dermatology, 2024 - search.ebscohost.com
This article, published in Experimental Dermatology, explores the potential link between the
NOD2 gene and hidradenitis suppurativa (HS) and inflammatory bowel disease (IBD). HS is …

Management of patients with hidradenitis suppurativa having underlying genetic variation: a systematic review and a call for precision medicine

D Mintoff, NP Pace, I Borg - Clinical and Experimental …, 2023 - academic.oup.com
Hidradenitis suppurativa (HS) is a chronic inflammatory condition of the pilosebaceous unit
characterized by inflammation and hyperkeratinization. A small but significant proportion of …