Role of reactive oxygen and nitrogen species in the vascular responses to inflammation

PR Kvietys, DN Granger - Free Radical Biology and Medicine, 2012 - Elsevier
Inflammation is a complex and potentially life-threatening condition that involves the
participation of a variety of chemical mediators, signaling pathways, and cell types. The …

[HTML][HTML] Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention

J Panés, M Perry, DN Granger - British journal of pharmacology, 1999 - ncbi.nlm.nih.gov
Abbreviations: AP-1, activation protein-1; CAM, cell adhesion molecule; ESL, E-selectin
ligand; ICAM, intercellular adhesion molecule; IL, interleukin; mAb, monoclonal antibody; NF …

Leukocyte-endothelial cell interactions: molecular mechanisms and implications in gastrointestinal disease

DN Granger - Gastroenterology, 1998 - Elsevier
Leukocyte-endothelial cell adhesion is now recognized to represent an early and rate-
limiting step in the leukocyte infiltration and accompanying tissue injury that is associated …

Characterization of a Helicobacter pylori neutrophil-activating protein

DJ Evans Jr, DG Evans, T Takemura… - Infection and …, 1995 - Am Soc Microbiol
Helicobacter pylori-associated gastritis is mainly an inflammatory cell response. In earlier
work we showed that activation of human neutrophils by a cell-free water extract of H. pylori …

Modulation of leukocyte–endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease

MB Grisham, DN Granger, DJ Lefer - Free radical biology and medicine, 1998 - Elsevier
Ischemia and reperfusion (I/R) are thought to play an important role in the pathophysiology
of ischemic diseases of the heart. It is now well appreciated that leukocyte–endothelial cell …

Molecular and cellular mechanisms involved in Helicobacter pylori-induced inflammation and oxidative stress

Y Naito, T Yoshikawa - Free Radical Biology and Medicine, 2002 - Elsevier
Helicobacter pylori (H. pylori)-infection leads to different clinical and pathological outcomes
in humans, including chronic gastritis, peptic ulcer disease, and gastric neoplasia. The key …

Helicobacter pylori binds von Willebrand factor and interacts with GPIb to induce platelet aggregation

MF Byrne, SW Kerrigan, PA Corcoran, JC Atherton… - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: Clinical studies have suggested an association between
cardiovascular disease and infection with Helicobacter pylori. We examined the effect of H …

Serum ferritin, hemoglobin, and Helicobacter pylori infection: a seroepidemiologic survey comprising 2794 Danish adults

N Milman, S Rosenstock, L Andersen, T Jørgensen… - Gastroenterology, 1998 - Elsevier
Background & Aims: Helicobacter pylori infection was recently associated with iron-
deficiency anemia. The aim of this study was to examine the relationship between H. pylori …

Helicobacter pyloriand gastric inflammation

K Bodger, JE Crabtree - British medical bulletin, 1998 - academic.oup.com
H. pylori infection leads to gastric inflammation, characterised histologically by surface
epithelial degeneration and infiltration of the gastric mucosa by acute and chronic …

Cutting edge: VacA, a vacuolating cytotoxin of Helicobacter pylori, directly activates mast cells for migration and production of proinflammatory cytokines

V Supajatura, H Ushio, A Wada, K Yahiro… - The Journal of …, 2002 - journals.aai.org
Mucosal mast cells strategically located at the optimal site interact with invading bacteria.
Presence of VacA, the virulent Helicobacter pylori cytotoxin, is correlated with the severity of …