Official international association for therapeutic drug monitoring and clinical toxicology guideline: development and validation of dried blood spot–based methods for …

S Capiau, H Veenhof, RA Koster… - Therapeutic drug …, 2019 - journals.lww.com
Dried blood spot (DBS) analysis has been introduced more and more into clinical practice to
facilitate Therapeutic Drug Monitoring (TDM). To assure the quality of bioanalytical methods …

Is the hematocrit still an issue in quantitative dried blood spot analysis?

S Velghe, L Delahaye, CP Stove - Journal of pharmaceutical and …, 2019 - Elsevier
Hematocrit-related issues remain a major barrier for (regulatory) acceptance of the classical
dried blood spot (DBS) analysis in the bioanalytical and clinical field. Lately, many attempts …

Alternative sampling devices to collect dried blood microsamples: state-of-the-art

L Delahaye, H Veenhof, BCP Koch… - Therapeutic drug …, 2021 - journals.lww.com
Dried blood spots (DBS) have been used in newborn screening programs for several years.
More recently, there has been growing interest in using DBS as a home sampling tool for the …

Emerging trends in paper spray mass spectrometry: Microsampling, storage, direct analysis, and applications

BS Frey, DE Damon… - Mass spectrometry …, 2020 - Wiley Online Library
Recent advancements in the sensitivity of chemical instrumentation have led to increased
interest in the use of microsamples for translational and biomedical research. Paper …

DropWise: current role and future perspectives of dried blood spots (DBS), blood microsampling, and their analysis in sports drug testing

M Thevis, K Walpurgis, A Thomas - Critical Reviews in Clinical …, 2023 - Taylor & Francis
For decades, blood testing has been an integral part of routine doping controls. The breadth
of information contained in blood samples has become considerably more accessible for …

Fully automated dried blood spot sample preparation enables the detection of lower molecular mass peptide and non-peptide doping agents by means of LC-HRMS

T Lange, A Thomas, K Walpurgis, M Thevis - Analytical and bioanalytical …, 2020 - Springer
The added value of dried blood spot (DBS) samples complementing the information
obtained from commonly routine doping control matrices is continuously increasing in sports …

Liquid chromatography-tandem mass spectrometry for therapeutic drug monitoring of immunosuppressants and creatinine from a single dried blood spot using the …

S Deprez, K Van Uytfanghe, CP Stove - Analytica Chimica Acta, 2023 - Elsevier
In recent years, a lot of attention has been given to a more patient-centric therapeutic drug
monitoring (TDM) of immunosuppressant drugs (tacrolimus, sirolimus, everolimus and …

Investigation of the 12-month stability of dried blood and urine spots applying untargeted UHPLC-MS metabolomic assays

EA Palmer, HJ Cooper, WB Dunn - Analytical chemistry, 2019 - ACS Publications
The use of dried blood spot (DBS) and dried urine spot (DUS) samples represents an
attractive opportunity for researchers in biomedical metabolomics to collect whole blood and …

Improved dried blood spot-based metabolomics: a targeted, broad-spectrum, single-injection method

K Li, JC Naviaux, JM Monk, L Wang, RK Naviaux - Metabolites, 2020 - mdpi.com
Dried blood spots (DBS) have proven to be a powerful sampling and storage method for
newborn screening and many other applications. However, DBS methods have not yet been …

Study of measurement of the alcohol biomarker phosphatidylethanol (PEth) in dried blood spot (DBS) samples and application of a volumetric DBS device

O Beck, NK Modén, S Seferaj, G Lenk, A Helander - Clinica chimica acta, 2018 - Elsevier
Phosphatidylethanol (PEth) is a group of phospholipids formed in cell membranes following
alcohol consumption. PEth measurement in whole blood samples is established as a …