In alcohol-induced liver disease (ALD) and in non-alcoholic fatty liver disease (NAFLD),
there are abnormal accumulations of fat in the liver. This phenomenon may be related to …

Oxysterol-binding protein (OSBP) and OSBP-related proteins (ORPs) constitute one of the
largest families of lipid-binding/transfer proteins (LTPs) in eukaryotes. The current view is …

Lipids must be correctly transported within the cell to the right place at the right time in order
to be fully functional. Non-vesicular lipid transport is mediated by so-called lipid transfer …

The endoplasmic reticulum (ER) forms direct membrane contact sites with the plasma
membrane (PM) in eukaryotic cells. These ER-PM contact sites play essential roles in lipid …

Extracellular membrane vesicles (EVs) are emerging as new vehicles in intercellular
communication, but how the biological information contained in EVs is shared between cells …

The VAP proteins are integral adaptor proteins of the endoplasmic reticulum (ER)
membrane that recruit a myriad of interacting partners to the ER surface. Through these …

Lipids are amphiphilic molecules that self-assemble to form biological membranes.
Thousands of lipid species coexist in the cell and, once combined, define organelle identity …

Lipids are precisely distributed in the eukaryotic cell where they help to define organelle
identity and function, in addition to their structural role. Once synthesized, many lipids must …

Phosphoinositide lipids (PPIn) are enriched in stearic‐and arachidonic acids (38: 4) but how
this enrichment is established and maintained during phospholipase C (PLC) activation is …

Vesicular trafficking and membrane fusion are well-characterized, versatile, and
sophisticated means of 'long range'intracellular protein and lipid delivery. Membrane contact …