The interests in intestinal epithelial tuft cells, their basic physiology, involvement in immune
responses and relevance for gut diseases, have increased dramatically over the last fifteen …

Objectives Decreased gut microbial gene richness (MGR) and compositional changes are
associated with adverse metabolism in overweight or moderate obesity, but lack …

Inflammatory bowel disease (IBD) is a chronic remitting disorder with increasing incidence
worldwide. The intestinal epithelial barrier plays a major role in IBD, contributing to its …

Emerging evidence indicates that gamma-aminobutyric acid (GABA) has many beneficial
effects such as ameliorating immune and inflammatory response. But, here we reported that …

Background Recent investigations have proposed the potential role of gamma-aminobutyric
acid (GABA) in regulating motility and immunity of the gastrointestinal system. Aims We …

The amoeba parasite Entamoeba histolytica is the causative agent of human amebiasis, an
enteropathic disease affecting millions of people worldwide. This ancient protozoan is an …

Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter. Recently, it is
considered to be a bioactive molecule with various health benefits. Ulcerative colitis (UC) is …

Methods Blood samples and colonic mucosal biopsies from clinically diagnosed IBS-D
patients and controls were collected. Levels of GABA were measured in serum samples …

Emerging evidence indicates that the gamma− aminobutyric acid type A receptor (GABAAR)
and Lactobacillus casei Zhang regulate colitis in a variety of ways, such as by participating …

Background Evidence have shown that Th1-and Th17-related cytokines are often elevated
in inflammatory bowel diseases (IBD). Hence, targeting Th17 cells or their effector cytokines …