The etiology of preeclampsia

E Jung, R Romero, L Yeo, N Gomez-Lopez… - American journal of …, 2022 - Elsevier
Preeclampsia is one of the “great obstetrical syndromes” in which multiple and sometimes
overlapping pathologic processes activate a common pathway consisting of endothelial cell …

Pre-eclampsia

LC Chappell, CA Cluver, S Tong - The Lancet, 2021 - thelancet.com
Pre-eclampsia is a multisystem pregnancy disorder characterised by variable degrees of
placental malperfusion, with release of soluble factors into the circulation. These factors …

Preeclampsia and eclampsia: the conceptual evolution of a syndrome

O Erez, R Romero, E Jung, P Chaemsaithong… - American journal of …, 2022 - Elsevier
Preeclampsia, one of the most enigmatic complications of pregnancy, is considered a
pregnancy-specific disorder caused by the placenta and cured only by delivery. This article …

[PDF][PDF] ISUOG Practice Guidelines: diagnosis and management of small-for-gestational-age fetus and fetal growth restriction

CC Lees, T Stampalija, AA Baschat… - Ultrasound in Obstetrics …, 2020 - arts.units.it
The International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) is a scientific
organization that encourages sound clinical practice, and high-quality teaching and …

Preeclampsia: pathophysiology, challenges, and perspectives

S Rana, E Lemoine, JP Granger… - Circulation …, 2019 - Am Heart Assoc
Hypertensive disorders of pregnancy—chronic hypertension, gestational hypertension, and
preeclampsia—are uniquely challenging as the pathology and its therapeutic management …

Developmental origins of metabolic diseases

DJ Hoffman, TL Powell, ES Barrett… - Physiological …, 2021 - journals.physiology.org
Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Pre-eclampsia: pathogenesis, novel diagnostics and therapies

EA Phipps, R Thadhani, T Benzing… - Nature Reviews …, 2019 - nature.com
Pre-eclampsia is a complication of pregnancy that is associated with substantial maternal
and fetal morbidity and mortality. The disease presents with new-onset hypertension and …

Preeclampsia: risk factors, diagnosis, management, and the cardiovascular impact on the offspring

R Fox, J Kitt, P Leeson, CYL Aye… - Journal of clinical …, 2019 - mdpi.com
Hypertensive disorders of pregnancy affect up to 10% of pregnancies worldwide, which
includes the 3%–5% of all pregnancies complicated by preeclampsia. Preeclampsia is …

[HTML][HTML] Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders

S Rana, SD Burke, SA Karumanchi - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia is a devastating medical complication of pregnancy that can lead to significant
maternal and fetal morbidity and mortality. It is currently believed that there is abnormal …

Endothelium structure and function in kidney health and disease

N Jourde-Chiche, F Fakhouri, L Dou, J Bellien… - Nature Reviews …, 2019 - nature.com
The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …