Chemoresistance remains the foremost challenge in cancer therapy. Targeting reactive
oxygen species (ROS) manipulation is a promising strategy in cancer treatment since tumor …

The central nervous system represents a complex environment in which glioblastoma
adapts skillfully, unleashing a series of mechanisms suitable for its efficient development …

Introduction Brain metastases (BrM), which commonly arise in patients with melanoma,
breast cancer and lung cancer, are associated with a poor clinical prognosis. In this context …

Glioblastoma (GBM), known as the most malignant and common primary brain tumor of the
central nervous system, has finite therapeutic options and a poor prognosis. Studies have …

Although the pathological significance of myeloid cell heterogeneity is still poorly
understood, new evidence indicates that distinct macrophage subsets are characterized by …

Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor.
Standard therapies, including surgical resection, chemoradiation, and tumor treating fields …

Ferroptosis is an iron-dependent form of cell death that results from excess lipid peroxidation
in cellular membranes. Within the last decade, physiological and pathological roles for …

Introduction Tissue diagnosis through stereotactic needle biopsy (SNB) is often needed prior
to laser interstitial thermal therapy (LITT). Whether these procedures should be performed in …

The clinical treatment of glioma remains relatively immature. Commonly used clinical
treatments for gliomas are surgery combined with chemotherapy and radiotherapy, but there …

Predicting the biological behavior and time to recurrence (TTR) of high-grade diffuse
gliomas (HGG) after maximum safe neurosurgical resection and combined radiation and …