Biological biomarkers of oral cancer
The oral squamous cell carcinoma (OSCC) 5 year survival rate of 41% has marginally
improved in the last few years, with less than a 1% improvement per year from 2005 to 2017 …
improved in the last few years, with less than a 1% improvement per year from 2005 to 2017 …
Data-centric artificial intelligence in oncology: a systematic review assessing data quality in machine learning models for head and neck cancer
Abstract Machine learning models have been increasingly considered to model head and
neck cancer outcomes for improved screening, diagnosis, treatment, and prognostication of …
neck cancer outcomes for improved screening, diagnosis, treatment, and prognostication of …
Clinical, morphologic and molecular heterogeneity of HPV-associated oropharyngeal cancer
The incidence of human papillomavirus-positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) is rising rapidly and has exceeded cervical cancer to become the most …
carcinoma (OPSCC) is rising rapidly and has exceeded cervical cancer to become the most …
Predicting HPV association using deep learning and regular H&E stains allows granular stratification of oropharyngeal cancer patients
S Klein, N Wuerdemann, I Demers, C Kopp… - npj Digital …, 2023 - nature.com
Abstract Human Papilloma Virus (HPV)-associated oropharyngeal squamous cell cancer
(OPSCC) represents an OPSCC subgroup with an overall good prognosis with a rising …
(OPSCC) represents an OPSCC subgroup with an overall good prognosis with a rising …
[HTML][HTML] The prognostic value of tumor-infiltrating lymphocytes in head and neck squamous cell carcinoma: A systematic review and meta-analysis
M Torri, A Sandell, A Al-Samadi - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is experiencing a rising incidence and
mortality worldwide, emphasizing the need for reliable prognostic markers. Tumor-infiltrating …
mortality worldwide, emphasizing the need for reliable prognostic markers. Tumor-infiltrating …
Phase I/II trial of metformin as a chemo-radiosensitizer in a head and neck cancer patient population
JO Kemnade, M Florez, A Sabichi, J Zhang, P Jhaveri… - Oral Oncology, 2023 - Elsevier
Objectives Retrospective studies have shown that head and neck squamous cell carcinoma
(HNSCC) patients taking metformin demonstrate superior survival compared to their …
(HNSCC) patients taking metformin demonstrate superior survival compared to their …
Machine learning driven index of tumor multinucleation correlates with survival and suppressed anti-tumor immunity in head and neck squamous cell carcinoma …
CF Koyuncu, MJ Frederick, LDR Thompson… - Oral Oncology, 2023 - Elsevier
Objectives Matching treatment intensity to tumor biology is critical to precision oncology for
head and neck squamous cell carcinoma (HNSCC) patients. We sought to identify biological …
head and neck squamous cell carcinoma (HNSCC) patients. We sought to identify biological …
Extracting interpretable features for pathologists using weakly supervised learning to predict p16 expression in oropharyngeal cancer
M Adachi, T Taki, N Sakamoto, M Kojima, A Hirao… - Scientific Reports, 2024 - nature.com
One drawback of existing artificial intelligence (AI)-based histopathological prediction
models is the lack of interpretability. The objective of this study is to extract p16-positive …
models is the lack of interpretability. The objective of this study is to extract p16-positive …
Moving from conventional to adaptive risk stratification for oropharyngeal cancer
VC Sandulache, RP Kirby, SY Lai - Frontiers in Oncology, 2024 - frontiersin.org
Oropharyngeal cancer (OPC) poses a complex therapeutic dilemma for patients and
oncologists alike, made worse by the epidemic increase in new cases associated with the …
oncologists alike, made worse by the epidemic increase in new cases associated with the …
[HTML][HTML] A novel computational pathology approach for identifying gene signatures prognostic of disease-free survival for papillary thyroid carcinomas
Introduction Papillary thyroid carcinoma (PTC) is the most prevalent form of thyroid cancer,
with the classical and follicular variants representing most cases. Despite generally …
with the classical and follicular variants representing most cases. Despite generally …