Response mechanisms of Saccharomyces cerevisiae to the stress factors present in lignocellulose hydrolysate and strategies for constructing robust strains

B Li, N Liu, X Zhao - Biotechnology for Biofuels and Bioproducts, 2022 - Springer
Bioconversion of lignocellulosic biomass to biofuels such as bioethanol and high value-
added products has attracted great interest in recent decades due to the carbon neutral …

Microbial production of riboflavin: biotechnological advances and perspectives

J You, X Pan, C Yang, Y Du, T Osire, T Yang… - Metabolic …, 2021 - Elsevier
Riboflavin is an essential nutrient for humans and animals, and its derivatives flavin
mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are cofactors in the cells …

Adenosine nucleotide biosynthesis and AMPK regulate adult life span and mediate the longevity benefit of caloric restriction in flies

D Stenesen, JM Suh, J Seo, K Yu, KS Lee, JS Kim… - Cell metabolism, 2013 - cell.com
A common thread among conserved life span regulators lies within intertwined roles in
metabolism and energy homeostasis. We show that heterozygous mutations of AMP …

A microarray-based genetic screen for yeast chronological aging factors

M Matecic, DL Smith Jr, X Pan, N Maqani… - PLoS …, 2010 - journals.plos.org
Model organisms have played an important role in the elucidation of multiple genes and
cellular processes that regulate aging. In this study we utilized the budding yeast …

Enhanced acetic acid stress tolerance and ethanol production in Saccharomyces cerevisiae by modulating expression of the de novo purine biosynthesis genes

MM Zhang, L Xiong, YJ Tang, MA Mehmood… - Biotechnology for …, 2019 - Springer
Background Yeast strains that are tolerant to multiple environmental stresses are highly
desired for various industrial applications. Despite great efforts in identifying key genes …

Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice

S Ferrari, M Sanguinetti, F De Bernardis… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Mitochondrial dysfunction is one of the possible mechanisms by which azole resistance can
occur in Candida glabrata. Cells with mitochondrial DNA deficiency (so-called “petite …

Biological sex and DNA repair deficiency drive Alzheimer's disease via systemic metabolic remodeling and brain mitochondrial dysfunction

TG Demarest, VR Varma, D Estrada, M Babbar… - Acta …, 2020 - Springer
Alzheimer's disease (AD) is an incurable neurodegenerative disease that is more prevalent
in women. The increased risk of AD in women is not well understood. It is well established …

Systematic approach for dissecting the molecular mechanisms of transcriptional regulation in bacteria

NM Belliveau, SL Barnes, WT Ireland… - Proceedings of the …, 2018 - National Acad Sciences
Gene regulation is one of the most ubiquitous processes in biology. However, while the
catalog of bacterial genomes continues to expand rapidly, we remain ignorant about how …

The PurR regulon in Escherichia coli K-12 MG1655

BK Cho, SA Federowicz, M Embree… - Nucleic acids …, 2011 - academic.oup.com
The PurR transcription factor plays a critical role in transcriptional regulation of purine
metabolism in enterobacteria. Here, we elucidate the role of PurR under exogenous …

Metschnikowia pulcherrima represses aerobic respiration in Saccharomyces cerevisiae suggesting a direct response to co-cultivation

A Mencher, P Morales, JA Curiel, R Gonzalez… - Food …, 2021 - Elsevier
The use of non-Saccharomyces species as starter cultures together with Saccharomyces
cerevisiae is becoming a common practice in the oenological industry to produce wines that …