Diverse pathogen-and damage-associated stresses drive inflammation via activation of the
multimolecular NLRP3–inflammasome complex. How the effects of diverse stimuli are …

Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has quickly spread worldwide and has affected …

Extracellular vesicles (EVs) have emerged as a promising platform for gene delivery owing
to their natural properties and phenomenal functions, being able to circumvent the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades most innate
immune responses but may still be vulnerable to some. Here, we systematically analyze the …

Abstract Motivation The Golgi apparatus has a key functional role in protein biosynthesis
within the eukaryotic cell with malfunction resulting in various neurodegenerative diseases …

Abstract Peroxynitrite (ONOO-), an endogenous reactive oxygen species (ROS), can cause
a variety of diseases in organisms at high levels. Golgi oxidative stress produces a large …

The dysregulation of NLRP3 inflammasome plays a critical role in pathogenesis of various
human inflammatory diseases, thus NLRP3 inflammasome activation must be tightly …

Regulating autophagy to control the homeostatic recycling process of cancer cells is a
promising anticancer strategy. Golgi apparatus is a substrate of autophagy but the Golgi …

Pathogenic intracellular bacteria, parasites and viruses have evolved sophisticated
mechanisms to manipulate mammalian host cells to serve as niches for persistence and …

For more than 3 decades, mounting evidence has associated porcine reproductive and
respiratory syndrome virus (PRRSV) infection with late-term abortions and stillbirths in sows …