Recent advances in organic near-infrared ratiometric small-molecule fluorescent probes

YL Qi, YZ Li, MJ Tan, FF Yuan, N Murthy… - Coordination Chemistry …, 2023 - Elsevier
The burgeoning organic near-infrared (NIR) ratiometric small-molecule fluorescent probes
with excellent merits have attracted great attention over the past few years. The traditional …

Small molecular fluorescent probes for Alzheimer's disease associated active species

F Tang, K Wang, X Liu, X Zhang, W Zhou… - … A European Journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and is the main
cause of dementia worldwide. As the pathogenesis of AD is quite complicated, there is …

Engineering fluorescent protein chromophores with an internal reference for high-fidelity ratiometric G4 imaging in living cells

JN Han, C Zhong, M Ge, S Kuang, Z Nie - Chemical Science, 2023 - pubs.rsc.org
G-quadruplexes (G4s) are significant nucleic acid secondary structures formed by guanine-
rich sequences. Many single-emission G4 fluorescent probes that are lit up by inhibiting …

AIE-based fluorescent micro-optical sectioning tomography for automatic 3D mapping of β-amyloid plaques in Tg mouse whole brain

YL Wang, T Luo, J Zhang, C Fan, X Li, C Li… - Chemical Engineering …, 2022 - Elsevier
Rapid verification and three-dimensional (3D) mapping of β-amyloid (Aβ) plaques in mouse
whole brain is of great significance in early diagnosis of Alzheimer's disease (AD) due to the …

Rational design of hydroxytricyanopyrrole-based probes with high affinity and rapid visualization for amyloid-β aggregates in vitro and in vivo

J Lv, J Gao, H Li, Z Yuan, N Dong - Chinese Chemical Letters, 2024 - Elsevier
As key biomarkers, amyloid-β (Aβ) plaques are frequently used to diagnose Alzheimer's
disease (AD). Although fluorescence imaging has proven to be effective in detecting these …

Lighting up self-quenching nanoaggregates with protein corona for simultaneous intraoperative imaging and photothermal theranostics of metastatic cancer

X Mu, W Feng, C Li, K Li, Y Li, X Jing, Y Lu… - Analytical …, 2022 - ACS Publications
Near-infrared (NIR) photothermal transduction agents (PTAs) with large rigid π-extended
and planar structures are prone to aggregate in a physiological environment where their …

Albumin-mediated molecular competition of supramolecular photosensitizers for NIR-II imaging-guided phototherapy

X Mu, Y Li, M Zhai, M Gao, W Feng, X Han, Y Wang… - Dyes and …, 2024 - Elsevier
Heptamethine cyanines (Cy7) typically exhibit strong near-infrared (NIR) fluorescence
signals when in monodisperse states, but their distinctive π-conjugated structure leads to …