Ferroptosis is a mechanism of regulated necrotic cell death characterized by iron-
dependent, lipid peroxidation-driven membrane destruction that can be inhibited by …

Superoxide is a primary oxygen radical that is produced when an oxygen molecule receives
one electron. Superoxide dismutase (SOD) plays a primary role in the cellular defense …

Reactive oxygen species‐(ROS‐) induced lipid peroxidation plays a critical role in cell death
including apoptosis, autophagy, and ferroptosis. This fundamental and conserved …

Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

Ferroptosis is an iron-dependent, non-apoptotic form of programmed cell death driven by
excessive lipid peroxidation (LPO). Mounting evidence suggests that the unique modality of …

Ferroptosis is a newly discovered type of cell death triggered by intracellular phospholipid
peroxidation that is morphologically, biologically and genetically distinct from other types of …

Background Ferroptosis is a newly defined form of regulated cell death characterized by the
iron-dependent accumulation of lipid peroxidation and is involved in various …

Ferroptosis, triggered by discoordination of iron, thiols and lipids, leads to the accumulation
of 15-hydroperoxy (Hp)-arachidonoyl-phosphatidylethanolamine (15-HpETE-PE), generated …

Ferroptotic death is the penalty for losing control over three processes—iron metabolism,
lipid peroxidation and thiol regulation—that are common in the pro-inflammatory …

Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …