Development of a cognitive function marker based on D-amino acid proportions using new chiral tandem LC-MS/MS systems

R Kimura, H Tsujimura, M Tsuchiya, S Soga, N Ota… - Scientific Reports, 2020 - nature.com
The incidence of dementia, a clinical symptom characterized by severe cognitive decline, is
increasing worldwide. Predictive biomarkers are therefore required for early identification …

Neuroprotective effects of Flavonoids: Endoplasmic reticulum as the target

B Amiri, M Yazdani Tabrizi, M Naziri, F Moradi… - Frontiers in …, 2024 - frontiersin.org
The incidence of neurological disorders, particularly age-related neurodegenerative
pathologies, exhibits an alarming upward trend, while current pharmacological interventions …

Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

J Liu, A Maisonial-Besset, B Wenzel, D Canitrot… - European Journal of …, 2017 - Elsevier
The increasing incidence of Alzheimer's disease (AD) worldwide is a major public health
problem. Current treatments provide only palliative solutions with significant side effects …

GC/MS‐Based Urine Metabolomics Study on the Ameliorative Effect of Xanthoceras sorbifolia Extract on Alzheimer's Disease in Mice

R Han, M Wang, L Wang, Y Zhang, X Li… - Evidence‐Based …, 2022 - Wiley Online Library
The cause of Alzheimer's disease, the most common type of dementia today, is still unclear,
and in current research, there are no drugs that work relatively well. Therefore, the study for …