Aminoacyl-tRNA synthetases (ARSs) are widely found in organisms, which can activate
amino acids and make them bind to tRNA through ester bond to form the corresponding …

Abdominal aortic aneurysms (AAAs) are highly lethal cardiovascular diseases without
effective medications. However, the molecular and signaling mechanisms remain unclear. A …

Neutrophil extracellular traps (NETs) play an important role in abdominal aortic aneurysm
(AAA) formation; however, the underlying molecular mechanisms remain unclear …

Oxidative stress plays a vital role in the development of abdominal aortic aneurysm (AAA).
DRD4 (dopamine D4 receptor) is involved in oxidative stress. Here, we reasoned that DRD4 …

Background As an inflammation-related cytokine, interleukin (IL)-5 has been reported to be
involved in the development of cardiovascular diseases, such as chronic heart failure and …

Abdominal aortic aneurysm (AAA) is a fatal vascular disease with insidious symptoms.
However, the mechanism behind its development remains unclear. The transient receptor …

The pathogenesis of abdominal aortic aneurysm (AAA) includes inflammatory responses,
matrix metalloproteinases (MMPs) degradation, VSMC apoptosis, oxidative stress, and …

Aminoacyl-tRNA synthetases are essential enzymes for the accurate translation of genetic
information. IARS1 and IARS2 are isoleucyl-tRNA synthetases functioning in the cytoplasm …

Abdominal aortic aneurysm (AAA) is a potentially life-threatening disease that is common in
the aging population. Currently, there are no approved diagnostic biomarkers or therapeutic …

Aminoacyl-tRNA synthetases (ARSs) have evolved to acquire various additional domains.
These domains allow ARSs to communicate with other cellular proteins in order to promote …