Innovative and rapid antimicrobial susceptibility testing systems

A van Belkum, CAD Burnham, JWA Rossen… - Nature Reviews …, 2020 - nature.com
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …

Cell-based biosensors: Recent trends, challenges and future perspectives

N Gupta, V Renugopalakrishnan, D Liepmann… - Biosensors and …, 2019 - Elsevier
Existing at the interface of biology and electronics, living cells have been in use as
biorecognition elements (bioreceptors) in biosensors since the early 1970s. They are an …

A fast impedance-based antimicrobial susceptibility test

DC Spencer, TF Paton, KT Mulroney, TJJ Inglis… - Nature …, 2020 - nature.com
There is an urgent need to develop simple and fast antimicrobial susceptibility tests (ASTs)
that allow informed prescribing of antibiotics. Here, we describe a label-free AST that can …

Porous silicon-based photonic biosensors: Current status and emerging applications

S Arshavsky-Graham, N Massad-Ivanir… - Analytical …, 2018 - ACS Publications
Since its first demonstration as a promising material for molecular detection two decades
ago, porous silicon (PSi) has become a commercially viable optical biosensor platform …

Rapid methods for antimicrobial resistance diagnostics

GD Kaprou, I Bergšpica, EA Alexa, A Alvarez-Ordóñez… - Antibiotics, 2021 - mdpi.com
Antimicrobial resistance (AMR) is one of the most challenging threats in public health; thus,
there is a growing demand for methods and technologies that enable rapid antimicrobial …

Handyfuge microfluidic for on-site antibiotic susceptibility testing

S Li, C Wan, B Wang, D Chen, W Zeng… - Analytical …, 2023 - ACS Publications
Low-cost, rapid, and accurate acquisition of minimum inhibitory concentrations (MICs) is key
to limiting the development of antimicrobial resistance (AMR). Until now, conventional …

[HTML][HTML] How to accelerate antimicrobial susceptibility testing

EA Idelevich, K Becker - Clinical microbiology and infection, 2019 - Elsevier
Background Antimicrobial susceptibility testing (AST) results are crucial for timely
administration of effective antimicrobial treatment, and, thus, should be made available to …

Microfluidic technology for antibacterial resistance study and antibiotic susceptibility testing: review and perspective

N Qin, P Zhao, EA Ho, G Xin, CL Ren - ACS sensors, 2020 - ACS Publications
A review on microfluidic technology for antibacterial resistance study and antibiotic
susceptibility testing (AST) is presented here. Antibiotic resistance has become a global …

Enzyme-assisted nucleic acid detection for infectious disease diagnostics: moving toward the point-of-care

A Suea-Ngam, L Bezinge, B Mateescu, PD Howes… - ACS …, 2020 - ACS Publications
Driven by complex and interconnected factors, including population growth, climate change,
and geopolitics, infectious diseases represent one of the greatest healthcare challenges of …

Point-of-care for evaluating antimicrobial resistance through the adoption of functional materials

S Singh, A Numan, S Cinti - Analytical Chemistry, 2021 - ACS Publications
Modern medicine has adopted the term “antimicrobials”, favoring the term “antibiotic” to
emphasize the inclusion of antiviral, antifungal, and antiparasitic medications. However …