The neonatal Fc receptor for IgG (FcRn) has been well characterized in the transfer of
passive humoral immunity from a mother to her fetus. In addition, throughout life, FcRn …

How do functional foods affect human health? To answer this question it is important to
understand what happens when food is digested and taken up by the gastrointestinal (GI) …

The neonatal Fc receptor (FcRn) is expressed by cells of epithelial, endothelial and myeloid
lineages and performs multiple roles in adaptive immunity. Characterizing the FcRn/IgG …

Under physiologic conditions, significant amounts of plasma protein pass the renal filter and
are reabsorbed by proximal tubular cells, but it is not clear whether the endocytosed protein …

Colostrogenesis is a separate and unique phase of mammary epithelial cell activity
occurring in the weeks before parturition and rather abruptly ending after birth in the bovine …

Biological transport of intact proteins across epithelial cells has been documented for many
absorptive and secretory tissues. Immunoglobulins were some of the earliest studied …

Efforts have been made to extend the biological half-life of monoclonal antibody drugs
(mAbs) by increasing the affinity of mAb–neonatal Fc receptor (FcRn) binding; however …

Vaccination is the most efficient way to combat and prevent infectious diseases. However,
most vaccines are administered systemically and are ineffective in eliciting protective …

We identified 1219 articles published in 2006 that described work performed using
commercial optical biosensor platforms. It is interesting to witness how the biosensor market …

The role of the FcRn is fundamental in IgG metabolism. It is involved in transporting maternal
immunity and protects IgG from fast degradation throughout life. While the acquisition of the …