In animals, systemic control of metabolism is conducted by metabolic tissues and relies on
the regulated circulation of a plethora of molecules, such as hormones and lipoprotein …

Both life span and health span are influenced by genetic, environmental and lifestyle factors.
With the genetic influence on human life span estimated to be about 20–25%, epigenetic …

Abstract The Holocene (beginning around 12,000 years ago) encompassed some of the
most significant changes in human evolution, with far-reaching consequences for the …

Background & Aims The prevalence and aetiology of liver fibrosis vary over time and impact
racial/ethnic groups unevenly. This study measured time trends and identified factors …

Background The accumulation of ectopic fats is related to metabolic syndromes with insulin
resistance, which is considered as the first hit in obesity-related diseases. However …

Gene regulation by microRNAs (miRNAs) plays important roles in development, physiology,
and disease. miRNAs are an abundant class of noncoding RNAs that are generated through …

Precision nutrition is an emerging area of nutrition research, with primary focus on the
individual variability in response to dietary and lifestyle factors, which are mainly determined …

Background Domestication and introduction of dairy animals facilitated the permanent
human occupation of the Tibetan Plateau. Yet the history of dairy pastoralism in the Tibetan …

The burden of growing concern about the dysregulation of metabolic processes arises due
to complex interplay between environment and nutrition that has great impact on genetics …

Abstract Purpose of Review Non-coding RNAs (ncRNAs) including microRNAs (miRNAs)
and circular RNAs (circRNAs) are pivotal regulators of mRNA and protein expression that …