Uncovering the mysteries of hantavirus infections

A Vaheri, T Strandin, J Hepojoki, T Sironen… - Nature Reviews …, 2013 - nature.com
Hantaviruses are negative-sense single-stranded RNA viruses that infect many species of
rodents, shrews, moles and bats. Infection in these reservoir hosts is almost asymptomatic …

Liquid phase partitioning in virus replication: observations and opportunities

C Wu, AS Holehouse, DW Leung… - Annual Review of …, 2022 - annualreviews.org
Viruses frequently carry out replication in specialized compartments within cells. The effect
of these structures on virus replication is poorly understood. Recent research supports …

Orthobunyaviruses: recent genetic and structural insights

RM Elliott - Nature Reviews Microbiology, 2014 - nature.com
Orthobunyaviruses, which have small, tripartite, negative-sense RNA genomes and
structurally simple virions composed of just four proteins, can have devastating effects on …

Multifaceted roles for lipids in viral infection

NS Heaton, G Randall - Trends in microbiology, 2011 - cell.com
Viruses have evolved complex and dynamic interactions with their host cell. In recent years
we have gained insight into the expanding roles for host lipids in the virus life cycle. In …

Let's phase it: viruses are master architects of biomolecular condensates

SM Sagan, SC Weber - Trends in Biochemical sciences, 2023 - cell.com
Viruses compartmentalize their replication and assembly machinery to both evade detection
and concentrate the viral proteins and nucleic acids necessary for genome replication and …

Alphavirus nsP3 organizes into tubular scaffolds essential for infection and the cytoplasmic granule architecture

V Kril, M Hons, C Amadori, C Zimberger… - Nature …, 2024 - nature.com
Alphaviruses, such as chikungunya virus (CHIKV), are mosquito-borne viruses that
represent a significant threat to human health due to the current context of global warming …

Three-dimensional visualization of viral structure, entry, and replication underlying the spread of SARS-CoV-2

JW Saville, AM Berezuk, SS Srivastava… - Chemical …, 2022 - ACS Publications
The global spread of SARS-CoV-2 has proceeded at an unprecedented rate. Remarkably,
characterization of the virus using modern tools in structural biology has also progressed at …

Recent advances in the molecular and cellular biology of bunyaviruses

CT Walter, JN Barr - Journal of General Virology, 2011 - microbiologyresearch.org
The family Bunyaviridae of segmented, negative-stranded RNA viruses includes over 350
members that infect a bewildering variety of animals and plants. Many of these bunyaviruses …

Virus factories: biogenesis and structural design

IF de Castro, L Volonté, C Risco - Cellular microbiology, 2013 - Wiley Online Library
Replication and assembly of many viruses occur in specific intracellular compartments
known as 'virus factories'. Our knowledge of the biogenesis and architecture of these unique …

A Look into Bunyavirales Genomes: Functions of Non-Structural (NS) Proteins

SS Leventhal, D Wilson, H Feldmann, DW Hawman - Viruses, 2021 - mdpi.com
In 2016, the Bunyavirales order was established by the International Committee on
Taxonomy of Viruses (ICTV) to incorporate the increasing number of related viruses across …