SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions
PH Sugden, LJ McGuffin, A Clerk - Biochemical Journal, 2013 - portlandpress.com
The GCKIII (germinal centre kinase III) subfamily of the mammalian Ste20 (sterile 20)-like
group of serine/threonine protein kinases comprises SOK1 (Ste20-like/oxidant-stress …
group of serine/threonine protein kinases comprises SOK1 (Ste20-like/oxidant-stress …
Reelin-Disabled-1 signaling in neuronal migration: splicing takes the stage
Abstract Reelin-Disabled-1 (Dab1) signaling has a well-established role in regulating
neuronal migration during brain development. Binding of Reelin to its receptors induces …
neuronal migration during brain development. Binding of Reelin to its receptors induces …
[HTML][HTML] Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis
M Bracher-Smith, G Leonenko, E Baker, K Crawford… - Neurobiology of …, 2022 - Elsevier
The APOE-ε4 allele is known to predispose to amyloid deposition and consequently is
strongly associated with Alzheimer's disease (AD) risk. There is debate as to whether the …
strongly associated with Alzheimer's disease (AD) risk. There is debate as to whether the …
Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration
T Matsuki, J Chen, BW Howell - Neural development, 2013 - Springer
Background Neuronal migration involves the directional migration of immature neurons.
During much of the migration period these neurons are polarized with defined leading and …
During much of the migration period these neurons are polarized with defined leading and …
[HTML][HTML] Mammalian sterile20-like kinases: signalings and roles in central nervous system
Abstract Mammalian Sterile20-like (MST) kinases are located upstream in the mitogen-
activated protein kinase pathway, and play an important role in cell proliferation …
activated protein kinase pathway, and play an important role in cell proliferation …
Effects of the C57BL/6 strain background on tauopathy progression in the rTg4510 mouse model
RM Bailey, J Howard, J Knight, N Sahara… - Molecular …, 2014 - Springer
Background Cross-breeding of transgenic mice is commonly used to assess gene-gene
interactions, particularly in the context of disease. Strain background changes can influence …
interactions, particularly in the context of disease. Strain background changes can influence …
Functional enrichment analysis of three Alzheimer's disease genome-wide association studies identities DAB1 as a novel candidate liability/protective gene
To explore genetic contributions of Alzheimer's disease (AD) at the level of biological terms
and pathways, we analyzed three Caucasian population-based genome-wide association …
and pathways, we analyzed three Caucasian population-based genome-wide association …
The GCKIII Kinase Sps1 and the 14-3-3 Isoforms, Bmh1 and Bmh2, Cooperate to Ensure Proper Sporulation in Saccharomyces cerevisiae
CJ Slubowski, SM Paulissen, LS Huang - PLoS One, 2014 - journals.plos.org
Sporulation in the budding yeast Saccharomyces cerevisiae is a developmental program
initiated in response to nutritional deprivation. Sps1, a serine/threonine kinase, is required …
initiated in response to nutritional deprivation. Sps1, a serine/threonine kinase, is required …
Humanized tau mice with regionalized amyloid exhibit behavioral deficits but no pathological interaction
Alzheimer's disease (AD) researchers have struggled for decades to draw a causal link
between extracellular Aβ aggregation and intraneuronal accumulation of microtubule …
between extracellular Aβ aggregation and intraneuronal accumulation of microtubule …
[图书][B] Dietary supplements in health promotion
TC Wallace - 2015 - books.google.com
The supplement market continues to grow annually with more than half of the population
using these products for reasons spanning from health maintenance to disease prevention …
using these products for reasons spanning from health maintenance to disease prevention …