Reactive oxygen species and sperm cells

D Sanocka, M Kurpisz - Reproductive biology and endocrinology, 2004 - Springer
There is a dynamic interplay between pro-and anti-oxidant substances in human ejaculate.
Excessive reactive oxygen species (ROS) generation can overwhelm protective mechanism …

Dynamics of the mammalian sperm plasma membrane in the process of fertilization

FM Flesch, BM Gadella - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2000 - Elsevier
Sexual reproduction requires the fusion of sperm cell and oocyte during fertilization to
produce the diploid zygote. In mammals complex changes in the plasma membrane of the …

[HTML][HTML] Central role of soluble adenylyl cyclase and cAMP in sperm physiology

MG Buffone, EV Wertheimer, PE Visconti… - Biochimica Et Biophysica …, 2014 - Elsevier
Abstract Cyclic adenosine 3′, 5′-monophosphate (cAMP), the first second messenger to
be described, plays a central role in cell signaling in a wide variety of cell types. Over the last …

Mammalian sperm acrosome: formation, contents, and function

A Abou-Haila, DRP Tulsiani - Archives of biochemistry and biophysics, 2000 - Elsevier
Sperm–egg interaction is a carbohydrate-mediated species-specific event which initiates a
signal transduction cascade resulting in the exocytosis of sperm acrosomal contents (ie, the …

Ion channels in sperm physiology

A Darszon, P Labarca, T Nishigaki… - Physiological …, 1999 - journals.physiology.org
Fertilization is a matter of life or death. In animals of sexual reproduction, the appropriate
communication between mature and competent male and female gametes determines the …

[HTML][HTML] Ca2+-stores in sperm: their identities and functions

S Costello, F Michelangeli, K Nash… - Reproduction …, 2009 - ncbi.nlm.nih.gov
Intracellular Ca 2+ stores play a central role in the regulation of cellular [Ca 2+] i and the
generation of complex [Ca 2+] signals such as oscillations and waves. Ca 2+ signalling is of …

[PDF][PDF] Protein kinases in mammalian sperm capacitation and the acrosome reaction

H Breitbart, Z Naor - Reviews of reproduction, 1999 - researchgate.net
Binding to the zona pellucida of an egg stimulates the spermatozoon to undergo the
acrosome reaction, a process that enables it to penetrate the egg. Before this binding, the …

Intracellular calcium regulation in sperm capacitation and acrosomal reaction

H Breitbart - Molecular and cellular endocrinology, 2002 - Elsevier
Binding to the egg's zona pellucida stimulates the spermatozoon to undergo acrosome
reaction, a process which enables the sperm to penetrate the egg. Prior to this binding, the …

Remodeling of the actin cytoskeleton during mammalian sperm capacitation and acrosome reaction

E Brener, S Rubinstein, G Cohen… - Biology of …, 2003 - academic.oup.com
The sperm acrosome reaction and penetration of the egg follow zona pellucida binding only
if the sperm has previously undergone the poorly understood maturation process known as …

Nongenomic actions of steroid hormones in reproductive tissues

A Revelli, M Massobrio, J Tesarik - Endocrine reviews, 1998 - academic.oup.com
Nongenomic Actions of Steroid Hormones in Reproductive Tissues* | Endocrine Reviews |
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