Molecular electron microscopy: state of the art and current challenges
H Stahlberg, T Walz - ACS chemical biology, 2008 - ACS Publications
The objective of molecular electron microscopy (EM) is to use electron microscopes to
visualize the structure of biological molecules. This Review provides a brief overview of the …
visualize the structure of biological molecules. This Review provides a brief overview of the …
2dx—user-friendly image processing for 2D crystals
B Gipson, X Zeng, ZY Zhang, H Stahlberg - Journal of structural biology, 2007 - Elsevier
Electron crystallography determines the structure of two-dimensional (2D) membrane
protein crystals and other 2D crystal systems. Cryo-transmission electron microscopy …
protein crystals and other 2D crystal systems. Cryo-transmission electron microscopy …
Electron cryomicroscopy of membrane proteins: specimen preparation for two-dimensional crystals and single particles
I Schmidt-Krey, JL Rubinstein - Micron, 2011 - Elsevier
Membrane protein structure and function can be studied by two powerful and highly
complementary electron cryomicroscopy (cryo-EM) methods: electron crystallography of two …
complementary electron cryomicroscopy (cryo-EM) methods: electron crystallography of two …
Combining X-ray Crystallography and Molecular Modeling toward the Optimization of Pyrazolo[3,4-d]pyrimidines as Potent c-Src Inhibitors Active in Vivo against …
c-Src is a tyrosine kinase belonging to the Src-family kinases. It is overexpressed and/or
hyperactivated in a variety of cancer cells, thus its inhibition has been predicted to have …
hyperactivated in a variety of cancer cells, thus its inhibition has been predicted to have …
2dx_merge: data management and merging for 2D crystal images
B Gipson, X Zeng, H Stahlberg - Journal of structural biology, 2007 - Elsevier
Electron crystallography of membrane proteins determines the structure of membrane-
reconstituted and two-dimensionally (2D) crystallized membrane proteins by low-dose …
reconstituted and two-dimensionally (2D) crystallized membrane proteins by low-dose …
Cryo-electron microscopy of membrane proteins
KN Goldie, P Abeyrathne, F Kebbel, M Chami… - … : Methods and Protocols, 2014 - Springer
Electron crystallography is used to study membrane proteins in the form of planar, two-
dimensional (2D) crystals, or other crystalline arrays such as tubular crystals. This method …
dimensional (2D) crystals, or other crystalline arrays such as tubular crystals. This method …
Crystal image analysis using 2D synchrosqueezed transforms
We propose efficient algorithms based on a band-limited version of 2D synchrosqueezed
transforms to extract mesoscopic and microscopic information from atomic crystal images …
transforms to extract mesoscopic and microscopic information from atomic crystal images …
3D reconstruction of two-dimensional crystals
H Stahlberg, N Biyani, A Engel - Archives of biochemistry and biophysics, 2015 - Elsevier
Electron crystallography of two-dimensional (2D) crystals determines the structure of
membrane proteins in the lipid bilayer by imaging with cryo-electron microscopy and image …
membrane proteins in the lipid bilayer by imaging with cryo-electron microscopy and image …
[HTML][HTML] 2dx_automator: Implementation of a semiautomatic high-throughput high-resolution cryo-electron crystallography pipeline
The introduction of direct electron detectors (DED) to cryo-electron microscopy has
tremendously increased the signal-to-noise ratio (SNR) and quality of the recorded images …
tremendously increased the signal-to-noise ratio (SNR) and quality of the recorded images …
3D reconstruction from 2D crystal image and diffraction data
Electron crystallography of 2D protein crystals can determine the structure of membrane
embedded proteins at high resolution. Images or electron diffraction patterns are recorded …
embedded proteins at high resolution. Images or electron diffraction patterns are recorded …