There is an unmet need to develop low-cost, rapid and highly multiplexed diagnostic
technology platforms for quantitatively detecting blood biomarkers to advance clinical …

MicroRNAs (miRNAs) play essential roles in post-transcriptional gene expression and are
also found freely circulating in bodily fluids such as blood. Dysregulated miRNA signatures …

Small RNAs (sRNAs) are an important group of non-coding RNAs that have great potential
as diagnostic and prognostic biomarkers for treatment of a wide variety of diseases. The …

In recent decades, nanopores have become a promising diagnostic tool. Protein and solid-
state nanopores are increasingly used for both RNA/DNA sequencing and small molecule …

Recently, microRNAs gain a great interest in the bio-molecular field due to their fundamental
role in clinical diagnostics. In this chapter, we generally discussed the biogenesis of …

We developed a technology for detecting and quantifying trace nucleic acids using a
bracketing protocol designed to yield a copy number with approximately±20% accuracy …

Autism spectrum disorders (ASD) diagnostic procedure still lacks a uniform biological
marker. This review gathers the information on microRNAs (miRNAs) specifically as a …

A large portion of human genome was believed to be “useless” and termed as “junk DNA” in
the past, given that these sequences did not have any protein coding role. However, with …

Nanopores can serve as single molecule sensors. We exploited the MinION, a portable
nanopore device from Oxford Nanopore Technologies, and repurposed it to detect any …

We developed a technology for detecting and quantifying trace nucleic acids using a
bracketing protocol designed to yield a copy number with approximately±20% accuracy …