Quantitative imaging of lipid droplets in single cells

A Gupta, GF Dorlhiac, AM Streets - Analyst, 2019 - pubs.rsc.org
The combination of next generation sequencing (NGS) and automated liquid handling
platforms has led to a revolution in single-cell genomic studies. However, many molecules …

Quantification of lipid metabolism in living cells through the dynamics of lipid droplets measured by stimulated Raman scattering imaging

C Zhang, J Li, L Lan, JX Cheng - Analytical chemistry, 2017 - ACS Publications
Dysregulation of lipid metabolism is associated with many diseases including cancer. Lipid
droplet (LD), a ubiquitous organelle in mammalian cells, serves as a hub for lipid …

Opportunities and challenges in three-dimensional brown adipogenesis of stem cells

AM Unser, Y Tian, Y Xie - Biotechnology advances, 2015 - Elsevier
The formation of brown adipose tissue (BAT) via brown adipogenesis has become a notable
process due to its ability to expend energy as heat with implications in the treatment of …

Evaluating adipocyte differentiation of bone marrow-derived mesenchymal stem cells by a deep learning method for automatic lipid droplet counting

L Hassanlou, S Meshgini, E Alizadeh - Computers in Biology and Medicine, 2019 - Elsevier
Stem cells are a group of competent cells capable of self-renewal and differentiating into
osteogenic, chondrogenic, and adipogenic lineages. These cells provide the possibility of …

Fast Adipogenesis Tracking System (FATS)—a robust, high-throughput, automation-ready adipogenesis quantification technique

C Yuan, S Chakraborty, KK Chitta… - Stem cell research & …, 2019 - Springer
Adipogenesis is essential in in vitro experimentation to assess differentiation capability of
stem cells, and therefore, its accurate measurement is important. Quantitative analysis of …

Freely Available Tool (FAT) for automated quantification of lipid droplets in stained cells

DF Masone, AD Gojanovich, YR Frontini López… - 2017 - ri.conicet.gov.ar
In this study, wepropose an automatic procedure for digital image processing. Wedescribe a
method that can efficiently quantify and characterizelipid droplets distributions in different …

Detection and Counting of Lipid Droplets in Adipocyte Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells Using a Tiny Convolutional Network and …

L Hassanlou, S Meshgini, E Alizadeh… - 2019 9th International …, 2019 - ieeexplore.ieee.org
Stem cells are a bunch of cells that are considered as encouraging cells for treating patients
because of their ability to regenerate themselves and also their potential for differentiation …

[图书][B] Brown adipogenesis of mouse embryonic stem cells in alginate microstrands

AM Unser - 2015 - search.proquest.com
The ability of brown adipocytes (fat cells) to dissipate energy as heat shows great promise
for the treatment of obesity and other metabolic disorders. Employing pluripotent stem cells …

Multi-modal Analysis of Metabolic Enzyme Disruption in Adipocytes

JK Sims - 2015 - search.proquest.com
Obesity results from a chronic imbalance in caloric intake and expenditure. The excess
calories are stored mainly as lipids (triglycerides, TG), leading to an expansion of body fat or …