Importance Direct oral anticoagulant (DOAC)–associated intracranial hemorrhage (ICH) has
high morbidity and mortality. The safety and outcome data of DOAC reversal agents in ICH …

Natural glycosaminoglycans (GAGs) are arguably the most diverse collection of natural
products. Unfortunately, this bounty of structures remains untapped. Decades of research …

The factors that predispose an individual to a higher risk of death from COVID-19 are poorly
understood. The goal of the study was to identify factors associated with risk of death among …

Objectives Rivaroxaban (RXB), a novel Xa inhibitor having groundbreaking therapeutic
potential. However, this drug is associated with few limitations, including its …

Apixaban and rivaroxaban are the two most prescribed direct factor Xa inhibitors. With the
increased use of DOACs in real-world settings, safety and efficacy concerns have emerged …

Antibodies to phospholipids (aPL) and associated proteins are a hallmark in the diagnosis of
anti-phospholipid syndrome (APS). Those included in the classification criteria are the lupus …

This document is an update of the multidisciplinary document HEMOMAS, published in 2016
with the endorsement of the Spanish Scientific Societies of Anaesthesiology (SEDAR) …

Rivaroxaban (RXB), an oral direct factor Xa inhibitor, presents innovative therapeutic profile.
However, RXB has shown adverse effects, mainly due to pharmacokinetic limitations …

El presente documento supone una puesta al día del documento multidisciplinar
HEMOMAS, publicado en el año 2016 con el aval de las Sociedades Científicas Españolas …

Objective The aim of this study was to determine the severe bleeding safety of direct oral
anticoagulants (DOACs) for the prevention and treatment of venous thromboembolism …