Mitochondria are organelles that are able to adjust and respond to different stressors and
metabolic needs within a cell, showcasing their plasticity and dynamic nature. These …

Mitochondria are multifunctional subcellular organelles essential for cellular energy
homeostasis and apoptotic cell death. It is, therefore, crucial to maintain mitochondrial …

Abstract Changes in mitochondrial morphology are associated with nutrient utilization, but
the precise causalities and the underlying mechanisms remain unknown. Here, using …

Metabolic fitness of T cells is essential for their vitality, which is largely dependent on the
behavior of the mitochondria. The nature of mitochondrial behavior in tumor-infiltrating T …

Mitofusins reside on the outer mitochondrial membrane and regulate mitochondrial fusion, a
physiological process that impacts diverse cellular processes. Mitofusins are activated by …

Charcot-Marie-Tooth (CMT) is the most prevalent category of inherited neuropathy. The most
common inheritance pattern is autosomal dominant, though there also are X-linked and …

Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …

The importance of mitochondrial dynamics, the physiological process of mitochondrial fusion
and fission, in regulating diverse cellular functions and cellular fitness has been well …

Mitochondria are organized in the cell in the form of a dynamic, interconnected network.
Mitochondrial dynamics, regulated by mitochondrial fission, fusion, and trafficking, ensure …

The central functions fulfilled by mitochondria as both energy generators essential for tissue
homeostasis and gateways to programmed apoptotic and necrotic cell death mandate tight …