Vaginal microbiome: normalcy vs dysbiosis
VS Saraf, SA Sheikh, A Ahmad, PM Gillevet… - Archives of …, 2021 - Springer
It has been long understood that the vaginal microflora is crucial in maintaining a normal
physiological environment for the host and its involvement is deemed indispensable for …
physiological environment for the host and its involvement is deemed indispensable for …
The role of infection in miscarriage
S Giakoumelou, N Wheelhouse… - Human reproduction …, 2016 - academic.oup.com
BACKGROUND Miscarriage is the spontaneous loss of a pregnancy before 12 weeks (early
miscarriage) or from 12 to 24 weeks (late miscarriage) of gestation. Miscarriage occurs in …
miscarriage) or from 12 to 24 weeks (late miscarriage) of gestation. Miscarriage occurs in …
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22
Endogenous tryptophan (Trp) metabolites have an important role in mammalian gut immune
homeostasis, yet the potential contribution of Trp metabolites from resident microbiota has …
homeostasis, yet the potential contribution of Trp metabolites from resident microbiota has …
Lactobacillus iners: friend or foe?
The vaginal microbial community is typically characterized by abundant lactobacilli.
Lactobacillus iners, a fairly recently detected species, is frequently present in the vaginal …
Lactobacillus iners, a fairly recently detected species, is frequently present in the vaginal …
Risk factors for spontaneous preterm delivery
T Cobo, M Kacerovsky… - International Journal of …, 2020 - Wiley Online Library
Background There is a substantial variation in rates of preterm delivery between different
parts of the world. The understanding of these variations, as well as the biological …
parts of the world. The understanding of these variations, as well as the biological …
The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women
Background This study was undertaken to characterize the vaginal microbiota throughout
normal human pregnancy using sequence-based techniques. We compared the vaginal …
normal human pregnancy using sequence-based techniques. We compared the vaginal …
Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …
Lactobacilli dominance and vaginal pH: why is the human vaginal microbiome unique?
The human vaginal microbiome is dominated by bacteria from the genus Lactobacillus,
which create an acidic environment thought to protect women against sexually transmitted …
which create an acidic environment thought to protect women against sexually transmitted …
Mucins: a biologically relevant glycan barrier in mucosal protection
AP Corfield - Biochimica et Biophysica Acta (BBA)-General Subjects, 2015 - Elsevier
Background The mucins found as components of mucus gel layers at mucosal surfaces
throughout the body play roles in protection as part of the defensive barrier on an organ and …
throughout the body play roles in protection as part of the defensive barrier on an organ and …
Ecological dynamics of the vaginal microbiome in relation to health and disease
The bacterial composition of the vaginal microbiome is thought to be related to health and
disease states of women. This microbiome is particularly dynamic, with compositional …
disease states of women. This microbiome is particularly dynamic, with compositional …