Organoids are in vitro miniaturized and simplified model systems of organs that have gained
enormous interest for modelling tissue development and disease, and for personalized …

Most swimming bacteria are capable of following gradients of nutrients, signaling molecules
and other environmental factors that affect bacterial physiology. This tactic behavior became …

Cellular interactions in the tumor microenvironment (TME) significantly govern cancer
progression and drug response. The efficacy of clinical immunotherapies has fostered an …

The recent advances in in vitro 3D culture technologies, such as organoids, have opened
new avenues for the development of novel, more physiological human cancer models. Such …

Organoids are in vitro–cultured three-dimensional structures that recapitulate key aspects of
in vivo organs. They can be established from pluripotent stem cells and from adult stem …

Organoids are 3D in vitro culture systems derived from self-organizing stem cells. They can
recapitulate the in vivo architecture, functionality, and genetic signature of original tissues …

Bacteria have evolved many different signal transduction systems that sense signals and
generate a variety of responses. Generally, most abundant are transcriptional regulators …

Chemotaxis enables microorganisms to move according to chemical gradients. Although
this process requires substantial cellular energy, it also affords key physiological benefits …

Motile bacteria use chemotaxis to migrate towards environments that are favorable for
growth and survival. The signaling pathway that mediates this behavior is largely conserved …

The capacity of the 3D-organoid cultures to resemble a near-physiological tissue
organization and to mimic–to a certain degree–organ functionality, make organoids an …