Weight regain after weight loss is a substantial challenge in obesity therapeutics. Dieting leads to significant adaptations in the homeostatic system that controls body weight, which …
T Reinehr - Molecular and cellular endocrinology, 2010 - Elsevier
A moderate elevation of thyrotropin (TSH) concentrations, which is associated with triiodothyronine (T3) values in or slightly above the upper normal range, is frequently found …
Although weight loss can usually be achieved by restricting food intake, the majority of dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the …
H Pan, J Guo, Z Su - Physiology & behavior, 2014 - Elsevier
Obesity, which has developed into a global epidemic, is a risk factor in most chronic diseases and some forms of malignancy. The discovery of leptin in 1994 has opened a new …
This study examined the interaction of 2 diets (high protein, reduced carbohydrates vs. low protein, high carbohydrates) with exercise on body composition and blood lipids in women …
MA Michalaki, AG Vagenakis, AS Leonardou… - Thyroid, 2006 - liebertpub.com
Morbidly obese subjects may present with abnormal thyroid function tests but the reported data are scarce. Therefore, we studied the thyroid parameters in 144 morbidly obese …
CN Ochner, DM Barrios, CD Lee, FX Pi-Sunyer - Physiology & behavior, 2013 - Elsevier
Weight loss dieting remains the treatment of choice for the vast majority of obese individuals, despite the limited long-term success of behavioral weight loss interventions. The reasons …
LH Duntas, B Biondi - Thyroid, 2013 - liebertpub.com
Background: There is increasing evidence that changes in thyroid function are associated with obesity, a condition associated with a chronic low-grade state of inflammation …
ES Blomain, DA Dirhan, MA Valentino… - International …, 2013 - Wiley Online Library
Obesity is a world‐wide pandemic and its incidence is on the rise along with associated comorbidities. Currently, there are few effective therapies to combat obesity. The use of …