Cholecystokinin (CCK) is a peptide originally discovered in the gastrointestinal tract but also
found in high density in the mammalian brain. The C-terminal sulphated octapeptide …

Gastrin is an important stimulant of acid secretion by gastric parietal cells and is structurally
related to the peptide hormone cholecystokinin (CCK). The pharmacologic properties of the …

The gastrointestinal peptide hormone gastrin is responsible for initiating the release of
gastric acid in the stomach in response to the presence of food and/or humoral factors such …

We have developed a unique virtual human model of gastric acid secretion and its
regulation in which food provides a driving force. Food stimulus triggers neural activity in …

Many hormones bind to cell surface receptors and cause an increase in [Ca2+] i.[Ca2+] i
mediates a variety of cellular responses, such as contraction of skeletal, cardiac and smooth …

We present a comprehensive mathematical model describing Helicobacter pylori interaction
with the human gastric acid secretion system. We use the model to explore host and …

Abstract Inositol 1, 4, 5‐trisphosphate (InsP3) receptor immunoreactivity in SH‐SY5 Y
human neuroblastoma cells was monitored with a monoclonal antibody raised against the …

The cholecystokinin (CCK)-B receptor cloned from human brain was characterized as a
gastrin receptor by using heterologous expression systems of COS-7 cells and Xenopus …

1 The possibility that bradykinin‐or histamine‐stimulated inositol polyphosphate
accumulation may be regulated by protein kinase C (PKC) in bovine adrenal chromaffin …

The mechanism whereby gastrin-type receptor and muscarinic M3-type receptor regulate
free intracellular Ca2+ concentration ([Ca2+] i) was studied in rabbit gastric parietal cells …