Interplay between the brain and adipose tissue: a metabolic conversation

F Díaz-Castro, E Morselli, M Claret - EMBO reports, 2024 - embopress.org
The central nervous system and adipose tissue interact through complex communication.
This bidirectional signaling regulates metabolic functions. The hypothalamus, a key …

The endocannabinoid system in appetite regulation and treatment of obesity

M Kurtov, I Rubinić, R Likić - Pharmacology Research & …, 2024 - Wiley Online Library
The endocannabinoid system (ECS) is a complex cell‐signaling system that is responsible
for maintaining homeostasis by modulating various regulatory reactions in response to …

Cannabidiol treatment improves metabolic profile and decreases hypothalamic inflammation caused by maternal obesity

FS Rodrigues, J Jantsch, GF Fraga, VS Dias… - Frontiers in …, 2023 - frontiersin.org
Introduction The implications of maternal overnutrition on offspring metabolic and
neuroimmune development are well-known. Increasing evidence now suggests that …

Fatty acid amide hydrolase C385A polymorphism affects susceptibility to various diseases

L Hosseinzadeh Anvar, A Ahmadalipour - BioFactors, 2023 - Wiley Online Library
The endocannabinoid (eCB) system is an important neuromodulatory system with its
extensive network of receptors throughout the human body that has complex actions in the …

Effect of cannabis and subproducts on anthropometric measures: a systematic review and meta-analysis

MG Reis, AJF Ferreira, MH Sohouli… - International Journal of …, 2024 - nature.com
Background Obesity poses a significant public health challenge. Research has examined
the impact of cannabis and subproducts on health but varying results have hindered a …

Central regulation of brown fat thermogenesis in response to saturated or unsaturated long-chain fatty acids

A Fosch, M Rodriguez-Garcia, C Miralpeix… - International Journal of …, 2023 - mdpi.com
Sensing of long-chain fatty acids (LCFA) in the hypothalamus modulates energy balance,
and its disruption leads to obesity. To date, the effects of saturated or unsaturated LCFA on …

Whey protein hydrolysates improve high-fat-diet-induced obesity by modulating the brain–peripheral axis of GLP-1 through inhibition of DPP-4 function in mice

C Rai, P Priyadarshini - European Journal of Nutrition, 2023 - Springer
Purpose Obesity is a growing global health concern. Recent literature indicates a prominent
role of glucagon-like peptide-1 (GLP-1) in glucose metabolism and food intake. The …

[引用][C] Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years

M Maccarrone, V Di Marzo, J Gertsch, U Grether… - Pharmacological …, 2023 - ASPET

A Targeted, Bioinert LC–MS/MS Method for Sensitive, Comprehensive Analysis of Signaling Lipids

S Rubenzucker, MC Manke, R Lehmann… - Analytical …, 2024 - ACS Publications
Signaling lipids are key players in cellular processes. Despite their importance, no method
currently allows their comprehensive monitoring in one analytical run. Challenges include a …

Cannabidiol partially rescues behavioral, neuroinflammatory and endocannabinoid dysfunctions stemming from maternal obesity in the adult offspring

F da Silva Rodrigues, J Jantsch, G de Farias Fraga… - …, 2025 - Elsevier
Maternal obesity is known to increase the risk of psychiatric disorders, such as anxiety,
depression, schizophrenia and autism spectrum disorder in the offspring. While preventive …