The harmful use of alcohol has been estimated to cause approximately 3.3 million deaths
every year, corresponding to nearly 6% of all deaths globally. Therefore, the effective …

Alcoholic liver disease (ALD) is a leading cause of cirrhosis, liver cancer, and acute and
chronic liver failure and as such causes significant morbidity and mortality. While alcohol …

The liver is an important metabolic and detoxification organ and hence demands a large
amount of energy, which is mainly produced by the mitochondria. Liver tissues of patients …

The function of liver is highly dependent on mitochondria producing ATP for biosynthetic and
detoxifying properties. Accumulating evidence indicates that most hepatic disorders are …

Non-alcoholic fatty liver disease (NAFLD) has a growing prevalence in recent years. Its
association with cardiovascular disease has been intensively studied, and certain …

Alcohol is a major cause of liver injury, and there are currently no ideal pharmacological
reagents that can prevent or reverse this disease. Apigenin is one of the most common …

Oxidative stress is known to be an inseparable factor involved in the presentation of liver
disorders. Free radicals interfere with DNA, proteins, and lipids, which are crucial in liver …

Methods A systematic literature search of the main international databases was performed.
We looked for seminal and innovative papers published in main international languages. A …

Alcoholic liver disease (ALD) is a clinical-pathologic entity caused by the chronic excessive
consumption of alcohol. The disease includes a broad spectrum of anomalies at the cellular …

Background: Oxidative stress plays a crucial role in the development of alcoholic liver
disease (ALD), however effective pharmacological treatment for oxidative injury is still …