Recently, numerous organizations, including governmental regulatory agencies in the US
and abroad, have proposed using data from new approach methodologies (NAMs) for …

There is a growing awareness that the large number of environmental pollutants we are
exposed to on a daily basis are causing major health problems. Compared to traditional …

New approach methodologies (NAMs) that efficiently provide information about chemical
hazard without using whole animals are needed to accelerate the pace of chemical risk …

Per-and poly-fluoroalkyl substances (PFAS) are widely found in the environment because of
their extensive use and persistence. Although several PFAS are well studied, most lack …

Neonicotinoid pesticides, originally developed to target the insect nervous system, have
been reported to interact with human receptors and to activate rodent neurons. Therefore …

Per-and polyfluoroalkyl substances (PFAS) are some of the most prominent organic
contaminants in human blood. Although the toxicological implications of human exposure to …

Per-and polyfluoroalkyl substances (PFAS) are a wide range of chemicals that are used in a
variety of consumer and industrial products leading to direct human exposure. Many PFAS …

The adoption of a new technology into basic research, and industrial and clinical settings
requires rigorous testing to build confidence in the reproducibility, reliability, robustness, and …

Microphysiological systems are an emerging area of in vitro drug development, and their
independent evaluation is important for wide adoption and use. The primary goal of this …

The starting point of successful hazard assessment is the generation of unbiased and
trustworthy data. Conventional toxicity testing deals with extensive observations of …