Mitochondria are best known for their role in the generation of ATP by aerobic respiration.
Yet, research in the past half century has shown that they perform a much larger suite of …

Woese and Fox's 1977 paper on the discovery of the Archaea triggered a revolution in the
field of evolutionary biology by showing that life was divided into not only prokaryotes and …

Mitochondria retain bacterial traits due to their endosymbiotic origin, but host cells do not
recognize them as foreign because the organelles are sequestered. However, the regulated …

Cancers that appear pathologically similar often respond differently to the same drug
regimens. Methods to better match patients to drugs are in high demand. We demonstrate a …

The origin of eukaryotes has been defined as the major evolutionary transition since the
origin of life itself. Most hallmark traits of eukaryotes, such as their intricate intracellular …

The dichotomy that separates prokaryotic from eukaryotic cells runs deep. The transition
from pro-to eukaryote evolution is poorly understood due to a lack of reliable intermediate …

The resolution of the broad-scale tree of eukaryotes is constantly improving, but the
evolutionary origin of several major groups remains unknown. Resolving the phylogenetic …

The origin of the eukaryotic cell is unresolved,. Metagenomics sequencing has recently
identified several potential eukaryotic gene homologues in Asgard archaea,, consistent with …

This book presents a comprehensive overview of the science of the history of life.
Paleobiologists bring many analytical tools to bear in interpreting the fossil record and the …

The Martian surface is cold, dry, exposed to biologically harmful radiation and apparently
barren today. Nevertheless, there is clear geological evidence for warmer, wetter intervals in …