Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …

Background Patients with prostate cancer who have high-risk biochemical recurrence have
an increased risk of progression. The efficacy and safety of enzalutamide plus androgen …

Background Current standard of care for metastatic castration-sensitive prostate cancer
supplements androgen deprivation therapy with either docetaxel, second-generation …

Background Darolutamide is a potent androgen-receptor inhibitor that has been associated
with increased overall survival among patients with nonmetastatic, castration-resistant …

PURPOSE The first interim analysis of the phase III, randomized, placebo-controlled TITAN
study showed that apalutamide significantly improved overall survival (OS) and radiographic …

This review covers the last 80 years of remarkable progress in the development of
mineralocorticoid receptor (MR) antagonists (MRAs) from synthesis of the first …

The NCCN Guidelines for Prostate Cancer address staging and risk assessment after a
prostate cancer diagnosis and include management options for localized, regional, and …

PURPOSE For patients with metastatic hormone-sensitive prostate cancer, metastatic
burden affects outcome. We examined efficacy and safety from the ARASENS trial for …

Background Innovations in treatments, imaging, and molecular characterisation in advanced
prostate cancer have improved outcomes, but there are still many aspects of management …