In vitro and in vivo delivery of therapeutic proteins using cell penetrating peptides

A Bolhassani, BS Jafarzade, G Mardani - Peptides, 2017 - Elsevier
The failure of proteins to penetrate mammalian cells or target tumor cells restricts their value
as therapeutic tools in a variety of diseases such as cancers. Recently, protein transduction …

Cell penetrating peptides: the potent multi-cargo intracellular carriers

K Kardani, A Milani, S H. Shabani… - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …

Cell-penetrating peptides: efficient vectors for vaccine delivery

J Yang, Y Luo, MA Shibu, I Toth… - Current drug …, 2019 - ingentaconnect.com
Subunit vaccines are composed of pathogen fragments that, on their own, are generally
poorly immunogenic. Therefore, the incorporation of an immunostimulating agent, eg …

Targeted drug delivery in cervical cancer: Current perspectives

S Ghosh, P Jayaram, SP Kabekkodu… - European Journal of …, 2022 - Elsevier
Cervical cancer is preventable yet one of the most prevalent cancers among women around
the globe. Though regular screening has resulted in the decline in incidence, the disease …

[图书][B] CPP, cell-penetrating peptides

Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …

Cell penetrating peptide: A potent delivery system in vaccine development

B Hasannejad-Asl, F Pooresmaeil… - Frontiers in …, 2022 - frontiersin.org
One of the main obstacles to most medication administrations (such as the vaccine
constructs) is the cellular membrane's inadequate permeability, which reduces their …

[HTML][HTML] Liposomal formulations of a polyleucine–antigen conjugate as therapeutic vaccines against cervical cancer

FZ Firdaus, S Bartlett, WM Hussein, L Lu, Q Wright… - Pharmaceutics, 2023 - mdpi.com
Human papilloma virus (HPV) is responsible for all cases of cervical cancer. While
prophylactic vaccines are available, the development of peptide-based vaccines as a …

The world of cell penetrating: The future of medical applications

A Falanga, L Lombardi, E Galdiero… - Future Medicinal …, 2020 - Taylor & Francis
Cell-penetrating peptides present huge biomedical applications in a variety of pathologies,
thanks to their ability to penetrate membranes and carry a variety of cargoes inside cells …

Mechanistic insights into the efficacy of cell penetrating peptide-based cancer vaccines

M Grau, PR Walker, M Derouazi - Cellular and Molecular Life Sciences, 2018 - Springer
Immunotherapies are increasingly used to treat cancer, with some outstanding results.
Immunotherapy modalities include therapeutic vaccination to eliminate cancer cells through …

Uptake pathways of cell-penetrating peptides in the context of drug delivery, gene therapy, and vaccine development

M Dowaidar - Cellular Signalling, 2024 - Elsevier
Cell-penetrating peptides have been extensively utilized for the purpose of facilitating the
intracellular delivery of cargo that is impermeable to the cell membrane. The researchers …