Composing on-program triggers and on-demand stimuli into biosensor drug carriers in drug delivery systems for programmable arthritis therapy
Medication in arthritis therapies is complex because the inflammatory progression of
rheumatoid arthritis (RA) and osteoarthritis (OA) is intertwined and influenced by one …
rheumatoid arthritis (RA) and osteoarthritis (OA) is intertwined and influenced by one …
Nucleolin‑based targeting strategies in cancer treatment: Focus on cancer immunotherapy
S Thongchot, K Aksonnam… - International …, 2023 - spandidos-publications.com
The benefits of treating several types of cancers using immunotherapy have recently been
established. The overexpression of nucleolin (NCL) in a number of types of cancer provides …
established. The overexpression of nucleolin (NCL) in a number of types of cancer provides …
[HTML][HTML] A top-down approach to uncover the hidden ligandome of low-density lipoprotein receptor-related protein 1 in cartilage
K Yamamoto, C Scavenius, MM Meschis… - Matrix Biology, 2022 - Elsevier
The low-density lipoprotein receptor-related protein 1 (LRP1) is a cell-surface receptor
ubiquitously expressed in various tissues. It plays tissue-specific roles by mediating …
ubiquitously expressed in various tissues. It plays tissue-specific roles by mediating …
A Unique G-Quadruplex Aptamer: A Novel Approach for Cancer Cell Recognition, Cell Membrane Visualization, and RSV Infection Detection
CD Xiao, MQ Zhong, Y Gao, ZL Yang, MH Jia… - International Journal of …, 2023 - mdpi.com
Surface staining has emerged as a rapid technique for applying external stains to trace
cellular identities in diverse populations. In this study, we developed a distinctive aptamer …
cellular identities in diverse populations. In this study, we developed a distinctive aptamer …
Development of hybrid aptamers-engineered PROTACs for degrading VEGF165 in both tumor-and vascular endothelial cells
Z Feng, D Xie, F Qiu, J Huang, Z Wang… - European Journal of …, 2025 - Elsevier
Tumors and angiogenesis are connected through a complex interplay. VEGF165, generated
from both tumor and vascular endothelial cells, serves as a mutual benefit for both cell types …
from both tumor and vascular endothelial cells, serves as a mutual benefit for both cell types …
Limb expression 1‐like protein promotes epithelial–mesenchymal transition and epidermal growth factor receptor‐tyrosine kinase inhibitor resistance via nucleolin …
M Li, J Zhang, X Meng, B Liu, SM Xie, F Liu… - Cancer …, 2023 - Wiley Online Library
Limb expression 1‐like protein (LIX1L) might be an RNA‐binding protein involved in post‐
transcriptional regulation. However, little is known regarding the biological function and …
transcriptional regulation. However, little is known regarding the biological function and …
Uncovering the ligandome of low-density lipoprotein receptor-related protein 1 in cartilage: a top-down approach to identify therapeutic targets
K Yamamoto, C Scavenius, MM Meschis… - bioRxiv, 2022 - biorxiv.org
The low-density lipoprotein receptor-related protein 1 (LRP1) is a cell-surface receptor
ubiquitously expressed in adult tissues. It plays tissue-specific physiological roles by …
ubiquitously expressed in adult tissues. It plays tissue-specific physiological roles by …
[HTML][HTML] 核仁素在结肠癌组织中的表达及临床意义
曲竑宇， 李泽群， 刘学超， 李毅， 牛兆建 - Advances in Clinical …, 2024 - hanspub.org
目的: 核仁素(Nucleolin, NCL) 已被证明在肿瘤中发挥重要作用, 但结肠癌中NCL
表达情况尚不明确. 本研究旨在探究NCL 在结肠癌中的表达情况与结肠癌临床病理特征以及 …
表达情况尚不明确. 本研究旨在探究NCL 在结肠癌中的表达情况与结肠癌临床病理特征以及 …
Evaluating the Role of RUNX2 in Cancer and Its Potential as a Therapeutic Target
R Pulica, K Cohen-Solal, A Lasfar - Handbook of Cancer and Immunology, 2022 - Springer
RUNX2, the transcription factor of the RUNX family, plays a critical role in homeostasis and a
variety of pathological conditions, including cancer. RUNX2 was first described as a master …
variety of pathological conditions, including cancer. RUNX2 was first described as a master …