Research Priorities on the Role of α‐Synuclein in Parkinson's Disease Pathogenesis
Various forms of Parkinson's disease, including its common sporadic form, are characterized
by prominent α‐synuclein (αSyn) aggregation in affected brain regions. However, the role of …
by prominent α‐synuclein (αSyn) aggregation in affected brain regions. However, the role of …
Silent threats of lead-based paints in toys and households to children's health and development
Lead (Pb), a highly toxic heavy metal, poses a significant global health risk, particularly to
children. Widely used in paint manufacturing for its remarkable corrosion-resistance …
children. Widely used in paint manufacturing for its remarkable corrosion-resistance …
[HTML][HTML] Alpha Synuclein Toxicity and Non-Motor Parkinson's
GM Mazzotta, C Conte - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is a common multisystem neurodegenerative disorder affecting
1% of the population over the age of 60 years. The main neuropathological features of PD …
1% of the population over the age of 60 years. The main neuropathological features of PD …
Prenatal and early life lead exposure induced neurotoxicity
A Parithathvi, N Choudhari… - Human & Experimental …, 2024 - journals.sagepub.com
Lead (Pb) has become a major environmental contaminant. There are several ways in which
lead can enter the human body and cause toxic effects on human health. This review …
lead can enter the human body and cause toxic effects on human health. This review …
Lead specifically declines tyrosine hydroxylase activity to induce the onset of Parkinson's disease through disrupting dopamine biosynthesis in fly models
Y Niu, Y Pan, Y Wang, Y Fu, Z Zhao, L Kang - Environmental Pollution, 2024 - Elsevier
Parkinson's disease (PD) is one of the fastest-growing neurodegenerative diseases and has
been linked to the exposure to numerous environmental neurotoxins. Although lead (Pb) …
been linked to the exposure to numerous environmental neurotoxins. Although lead (Pb) …
Versatility of Caenorhabditis elegans as a Model Organism for Evaluating Foodborne Neurotoxins and Food Bioactive Compounds in Nutritional Neuroscience
IA Adedara, GCC Weis, CS Monteiro, FAA Soares… - Molecular …, 2025 - Springer
Epidemiological evidence has shown that the regular ingestion of vegetables and fruits is
associated with reduced risk of developing chronic diseases. The introduction of the 3Rs …
associated with reduced risk of developing chronic diseases. The introduction of the 3Rs …
Neurotoxic Chemistry: Unraveling the chemical mechanisms connecting environmental toxin exposure to neurological disorders
H Gouri, G Bhalla - Journal of Integrated Science and …, 2025 - pubs.thesciencein.org
The environmental pollution poses a serious global health risk, contributing to high morbidity
and mortality rates. Neurological disorders, such as Alzheimer's, Parkinson's …
and mortality rates. Neurological disorders, such as Alzheimer's, Parkinson's …
Association of single and combined effects of blood heavy metals with cognitive function in older adults of the United States: A cross-sectional study
N Wang, L Guo, M Shi, L Wang, Y Zhou, H Liu… - 2024 - researchsquare.com
Background Heavy metal exposure has been associated with various diseases. The
purpose of this study was to determine the single and combined effects between blood …
purpose of this study was to determine the single and combined effects between blood …