Therapeutic applications and biological activities of bacterial bioactive extracts

Z Abdelghani, N Hourani, Z Zaidan, G Dbaibo… - Archives of …, 2021 - Springer
Bacteria are rich in a wide variety of secondary metabolites, such as pigments, alkaloids,
antibiotics, and others. These bioactive microbial products serve a great application in …

Mesenchymal stem cells could be considered as a candidate for further studies in cell-based therapy of Alzheimer's disease via targeting the signaling pathways

R Farahzadi, E Fathi, I Vietor - ACS chemical neuroscience, 2020 - ACS Publications
Mesenchymal stem cells (MSCs) are of particular interest because of their potential in
regenerative medicine. Stem cell-based therapies cast a new hope for neurodegenerative …

Cytokines secreted from bone marrow derived mesenchymal stem cells promote apoptosis and change cell cycle distribution of K562 cell line as clinical agent in cell …

E Fathi, R Farahzadi, B Valipour, Z Sanaat - PloS one, 2019 - journals.plos.org
Mesenchymal stem cells (MSCs) are of special interest due their potential clinical use in cell-
based therapy. Therapies engaging MSCs are showing increasing promise in the cancer …

Cardiac differentiation of bone-marrow-resident c-kit+ stem cells by L-carnitine increases through secretion of VEGF, IL6, IGF-1, and TGF-β as clinical agents in …

E Fathi, R Farahzadi, I Vietor, S Javanmardi - Journal of biosciences, 2020 - Springer
The idea of regenerating lost myocardium via cell-based therapies remains as highly
considerable. C-kit+ stem/progenitor cells are represented to be suitable candidates for …

[HTML][HTML] Interleukin-6,-8, and TGF-β secreted from mesenchymal stem cells show functional role in reduction of telomerase activity of leukemia cell via Wnt5a/β-catenin …

E Fathi, B Valipour, Z Sanaat… - Advanced …, 2020 - ncbi.nlm.nih.gov
Purpose: The effect of mesenchymal stem cells (MSCs) on the immortality features of
malignant cells, such as hematologic cancerous cells, are controversial, and the associated …

Bioactive potential of several actinobacteria isolated from microbiologically barely explored desert habitat, Saudi Arabia

MS Almuhayawi, MSM Mohamed, M Abdel-Mawgoud… - Biology, 2021 - mdpi.com
Simple Summary Bioactive natural products have been regarded as promising tools for
treatment of various ailments. Among natural sources, actinomycetes have been widely …

An overview on natural product from endophytic actinomycetes

GN Rajivgandhi, RTV Vimala, G Ramachandran… - Natural Products from …, 2022 - Springer
In recent years, all the chemical-mediated compounds, drugs, and other compounds are
inactivated due to the development of resistant effect. For this reason, there is an urgent …

Neoantimycin F, a Streptomyces-Derived Natural Product Induces Mitochondria-Related Apoptotic Death in Human Non-Small Cell Lung Cancer Cells

L Liu, H Zhu, W Wu, Y Shen, X Lin, Y Wu… - Frontiers in …, 2019 - frontiersin.org
Streptomyces-derived natural products have been become a major focus of anti-tumor drug
discovery studies. Neoantimycin F (NAT-F), was isolated from Streptomyces conglobatus by …

Bioactivity assessment of potentially active actinomycetes from rhizospheric soil

N Kumari, E Menghani, R Mithal - 2020 - nopr.niscpr.res.in
Soil organisms have been serving as therapeutic potent components as they produce many
bioactive natural products or secondary metabolites which act as antibiotics to fight against …

8-Hydroxyquinoline a natural chelating agent from Streptomyces spp. inhibits A549 lung cancer cell lines via BCL2/STAT3 regulating pathways

JD Balthazar, MP Soosaimanickam… - World Journal of …, 2022 - Springer
Biomolecules from Streptomyces spp. are emerging sources of natural drugs and have been
focused on over the decade. The discovery of bioactive chemotherapeutic molecules from …