Cellular membranes function as permeability barriers that separate cells from the external
environment or partition cells into distinct compartments. These membranes are lipid …

Cell membranes contain a large variety of lipid types and are crowded with proteins,
endowing them with the plasticity needed to fulfill their key roles in cell functioning. The …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

In eukaryotic membranes, type IV P-type adenosine triphosphatases (P4-ATPases) mediate
the translocation of phospholipids from the outer to the inner leaflet and maintain lipid …

Abstract Type 4 P-type ATPases (P4-ATPases) are lipid flippases that drive the active
transport of phospholipids from exoplasmic or luminal leaflets to cytosolic leaflets of …

Cellular membranes exhibit a fascinating variety of different morphologies, which are
continuously remodeled by transformations of membrane shape and topology. This …

The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …

Matrix-assisted laser desorption and ionization (MALDI) mass spectrometry (MS) is an
indispensable tool in modern lipid research since it is fast, sensitive, tolerates sample …

We present a comparative all-atom molecular dynamics simulation study of 18
biomembrane systems with lipid compositions corresponding to eukaryotic, bacterial, and …

Cerebral small vessel diseases (SVDs) are a central link between stroke and dementia—two
comorbidities without specific treatments. Despite the emerging consensus that SVDs are …